Evidence map›Paper›PMID 40668943›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2025

Diagnostic accuracy differences in detecting wound maceration between humans and artificial intelligence: the role of human expertise revisited.

Florian Kücking, Ursula H Hübner, Dorothee Busch

Abstract readComparative Study
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Clinical decision-making and artificial intelligence.Journal of the American Medical Informatics Association : JAMIA · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Florian KückingResearch Center of Health and Social Informatics, Osnabrück University of Applied Sciences, 49009 Osnabrück, Germany.ORCID 0009-0005-0808-6552
Ursula H HübnerResearch Center of Health and Social Informatics, Osnabrück University of Applied Sciences, 49009 Osnabrück, Germany.
Dorothee BuschResearch Center of Health and Social Informatics, Osnabrück University of Applied Sciences, 49009 Osnabrück, Germany.

Funding

Career Lab Hochschule OsnabrückCarLaFederal Ministry of Education and Research 03FHP180AFederal Ministry of Education and Research (BMBF) 03FHP180ALower Saxony Ministry of Science and Culture ZN3491Verkürzte Zeit bis zur Heilung durch mehr Evidenz mittels augmentierter Intelligenz 16SV8617Verkürzte Zeit bis zur Heilung durch mehr Evidenz mittels augmentierter Intelligenz (ZIEL) 16SV8617ZLGZukunftslabor Digitalisierung Gesundheit
6 · The paper itself

Abstract

objectiveThis study aims to compare the diagnostic abilities of humans in wound image assessment with those of an AI-based model, examine how "expertise" affects clinicians' diagnostic performance, and investigate the heterogeneity in clinical judgments. MATERIALS AND

methodsA total of 481 healthcare professionals completed a diagnostic task involving 30 chronic wound images with and without maceration. A convolutional neural network (CNN) classification model performed the same task. To predict human accuracy, participants' "expertise," ie, pertinent formal qualification, work experience, self-confidence, and wound focus, was analyzed in a regression analysis. Human interrater reliability was calculated.

resultsHuman participants achieved an average accuracy of 79.3% and a maximum accuracy of 85% in the formally qualified group. Achieving 90% accuracy, the CNN performed better but not significantly. Pertinent formal qualification (β  =  0.083, P < .001) and diagnostic self-confidence (β  =  0.015, P = .002) significantly predicted human accuracy, while work experience and focus on wound care had no effect (R2 = 24.3%). Overall interrater reliability was "fair" (Kappa = 0.391). DISCUSSION: Among the "expertise"-related factors, only the qualification and self-confidence variables influenced diagnostic accuracy. These findings challenge previous assumptions about work experience or job titles defining "expertise" and influencing human diagnostic performance.

conclusionThis study offers guidance to future studies when comparing human expert and AI task performance. However, to explain human diagnostic accuracy, "expertise" may only serve as one correlate, while additional factors need further research.

Indexed as

Artificial IntelligenceClinical CompetenceNeural Networks, ComputerWounds and InjuriesAdultFemaleHumansMaleReproducibility of Resultsartificial intelligencediagnostic accuracyhumaninterrater-reliabilitywound healingwound images

Identifiers

PMID40668943
PMCPMC12361858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.