Evidence map›Paper›PMID 40668835›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

α-glucan remodeling by GH13-domain enzymes shapes fungal cell wall architecture.

Anand Jacob, Alaina H Willet, Maya G Igarashi, Mustapha El Hariri El Nokab, Lesley A Turner, Abdulrahman Khalid A Alsanad, Tuo Wang, Kathleen L Gould

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. α-1,3-Glucan-Driven Remodeling of the Conidial Cell Wall in anJournal of the American Chemical Society · 2026
    Article
  6. Comparative Genomics Reveals Host-Specific Adaptation ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  7. Chaotropic Ions Reshape the Cell Wall of the Obligate HalophilebioRxiv : the preprint server for biology · 2026
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Anand Jacob *Department of Chemistry, Michigan State University, East Lansing, MI 48824.ORCID 0009-0009-7179-7460
Alaina H Willet *Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232.ORCID 0000-0002-0163-4772
Maya G IgarashiDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232.ORCID 0000-0003-3727-5473
Mustapha El Hariri El NokabDepartment of Chemistry, Michigan State University, East Lansing, MI 48824.ORCID 0000-0002-9211-427X
Lesley A TurnerDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232.ORCID 0009-0007-9663-2668
Abdulrahman Khalid A AlsanadDepartment of Chemistry, Michigan State University, East Lansing, MI 48824.
Tuo WangDepartment of Chemistry, Michigan State University, East Lansing, MI 48824.ORCID 0000-0002-1801-924X
Kathleen L GouldDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232.ORCID 0000-0002-3810-4070

Funding

Regulation of cytokinesisR35GM131799 · NIGMS · VANDERBILT UNIVERSITY · PI Kathleen L Gould · 2019 to 2026
$6.4M
Revealing the Cell Wall Organization of Fungal Pathogens and Structural Responses to Antifungal Drugs Using Cellular Solid-State NMRR01AI173270 · NIAID · MICHIGAN STATE UNIVERSITY · PI Tuo Wang · 2023 to 2026
$1.5M
Conventional 200 keV Transmission Electron MicroscopeS10OD034315 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JEROME, WALTER G · 2023 to 2023
$597k
Acquisition of a Leica high pressure freezer for the cryo-based electron microscopy techniquesS10MH137068 · NIMH · VANDERBILT UNIVERSITY · PI KRYSTOFIAK, EVAN · 2024 to 2024
$489k
Acquisition of a Leica ARTOS 3D UltramicrotomeR24OD037694 · OD · VANDERBILT UNIVERSITY · PI KRYSTOFIAK, EVAN · 2024 to 2024
$139k
HHS | NIH (NIH) R01AI173270HHS | NIH (NIH) R35GM131799NIAID NIH HHS R01 AI173270NIGMS NIH HHS R35 GM131799NIH HHS R24 OD037694NIH HHS S10 OD034315NIMH NIH HHS S10 MH137068
6 · The paper itself

Abstract

Cell walls are critical structures of fungi, bacteria, and plants, providing mechanical strength, maintaining shape, and protecting cells from environmental stress. In the fission yeast

Indexed as

Cell WallGlucansGlucosyltransferasesSchizosaccharomycesSchizosaccharomyces pombe ProteinsGalactoseMannansMutationalpha-1,3-glucangalactomannanGalactoseGlucansglucan synthaseGlucosyltransferasesMannansSchizosaccharomyces pombe Proteinsamylasecell divisionSchizosaccharomyces pombesolid-state NMRα-glucan

Identifiers

PMID40668835
PMCPMC12305055

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.