Evidence map›Paper›PMID 40668771›Full record

Trial reportPloS one2025

Walking cadence as a measure of activity intensity and impact on functional capacity for prefrail and frail older adults.

Daniel S Rubin, Anthony Hung, Emi Yamamoto, Donald Hedeker, David E Conroy, Megan Huisingh-Scheetz, Jennifer S Brach, Nancy W Glynn, Margaret K Danilovich

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniel S RubinDepartment of Anesthesia and Critical Care, University of Chicago, Chicago, Illinois, United States of America.ORCID https://orcid.org/0000-0002-0490-1186
Anthony HungPritzker School of Medicine, University of Chicago, Chicago, Illinois, United States of America.
Emi YamamotoPritzker School of Medicine, University of Chicago, Chicago, Illinois, United States of America.
Donald HedekerDepartment of Public Health Sciences, University of Chicago, Chicago, Illinois, United States of America.
David E ConroySchool of Kinesiology, University of Michigan. Ann Arbor, Michigan, United States of America.
Megan Huisingh-ScheetzDepartment of Medicine, Section of Geriatrics, University of Chicago, Chicago, Illinois, United States of America.
Jennifer S BrachDepartment of Physical Therapy, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Nancy W GlynnSchool of Public Health, Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.ORCID https://orcid.org/0000-0003-2265-0162
Margaret K DanilovichLeonard Schanfield Research Institute, CJE Senior Life, Chicago, Illinois, United States of America.

Funding

Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
The Effect of High Intensity Walking on FrailtyR01AG060162 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DANILOVICH, MARGARET K · 2018 to 2021
$1.3M
At-home gait-cadence functional assessment and recovery trajectory for older adults undergoing major abdominal surgeryR03AG078957 · NIA · UNIVERSITY OF CHICAGO · PI RUBIN, DANIEL STEVEN · 2022 to 2023
$328k
NIA NIH HHS R01 AG060162NIA NIH HHS R03 AG078957NIEHS NIH HHS P30 ES027792
6 · The paper itself

Abstract

Walking cadence has been suggested as a measure of activity intensity; however, it remains uncertain if prefrail and frail older adults can increase their walking cadence and if doing so leads to improvements in functional capacity. We aimed to determine if cadence can be increased and if this leads to improvement in functional capacity in prefrail and frail older adults. We performed a secondary data analysis of a walking intervention in prefrail and frail older adults living in retirement communities. Patients were randomized to Casual Speed Walking (CSW) and High-Intensity Walking (HIW) groups. Our primary outcome was improvement in 6-minute walk test distance above the minimally clinical important difference. We performed linear and logistic mixed-effects regressions to analyze our aims. 102 participants were included in the final analysis with 56 in the CSW group and 46 in the HIW group. Participants in the HIW group increased their walking cadence as compared to the CSW group during the intervention (HIW 100[88, 111] steps/min vs. CSW 77[65, 86] steps/min; P < 0.001). Participants that increased their walking cadence demonstrated an increased odds of improvement in their 6-minute walk test minimum clinically important difference (OR: 0.11, 95% CI: 0.033, 0.18; p = 0.005). Older adults can increase their walking cadence and walking cadence can serve as a surrogate measure of activity intensity during walking interventions. An increase of 14 steps/minute from their comfortable walking cadence increased the odds of improvement in 6-minute walk test minimum clinically important difference.

Indexed as

Frail ElderlyWalkingAgedAged, 80 and overFemaleGeriatric AssessmentHumansMaleWalking SpeedWalk Test

Identifiers

PMID40668771
PMCPMC12266393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.