Evidence map›Paper›PMID 40668671›Full record

ArticleEnvironmental science & technology2025

The Role and Phagocytic Mechanisms of Alveolar Macrophages in Inflammatory Responses Induced by Diesel Exhaust Particles.

Dongyang Han, Renzhen Peng, Bin Pan, Yuanting Xie, Wenpu Shao, Xinyi Fang, Jingyu Li, Xiaoqing Hong, Wenyue Tu, Janina Muller-Deile and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Dongyang HanDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China.
Renzhen PengDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China.
Bin PanDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China.
Yuanting XieDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China.
Wenpu ShaoDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China.
Xinyi FangDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China.
Jingyu LiDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China.
Xiaoqing HongDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China.
Wenyue TuDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China.
Janina Muller-DeileDepartment of Nephrology, Friedrich Alexander Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
Yaning ZhuDepartment of Pathology, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huaian 223399, China.
Weihua LiNHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), School of Pharmacy, Fudan University, Shanghai 200032, China.
Haidong KanDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China.ORCID 0000-0002-1871-8999
Zhekang YingDepartment of Medicine Cardiology Division, University of Maryland School of Medicine, Baltimore, Maryland 21201, United States.
Yanyi XuDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China.ORCID 0000-0003-0270-2017

Funding

Olfactory dysfunction as predictor of PM2.5 exposure progression to dementiaRF1AG093965 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI WU, JUNFANG, YING, ZHEKANG · 2025 to 2025
$3.3M
Mechanism for Programming of Offspring Adiposity by Maternal PM2.5 ExposureR01ES032290 · NIEHS · UNIVERSITY OF MARYLAND BALTIMORE · PI YING, ZHEKANG, YU, LIQING · 2021 to 2025
$3.1M
NIA NIH HHS RF1 AG093965NIEHS NIH HHS R01 ES032290
6 · The paper itself

Abstract

Alveolar macrophages, the most abundant innate immune cells in the distal lung parenchyma, are not only essential for maintaining pulmonary homeostasis but also orchestrate pulmonary and thus systemic responses to ambient particulate matter. However, their specific role in the development of adverse health effects related to ambient fine particulate matter (PM

Indexed as

Macrophages, AlveolarVehicle EmissionsAnimalsInflammationMiceParticulate MatterPhagocytosisParticulate MatterVehicle Emissionsalveolar macrophagesdiesel exhaust particlesinflammation responsemacrophage scavenger receptor 1phagocytosis

Identifiers

PMID40668671
PMCPMC12969937

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.