Evidence map›Paper›PMID 40668458›Full record

SynthesisAIDS and behavior2025

Assessing the Effectiveness of Data-to-Care Strategies for Improving HIV Care Outcomes: A Systematic Review.

Kristin Tansil Roberts, Mary Mullins, Darrel H Higa, Linda J Koenig, Megan Mallett, Megan Wichser, Christa L Denard, Jayleen Gunn, Miriam A M Nji, Briana Nguyen and 4 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in AIDS and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kristin Tansil RobertsTranslation and Evaluation Branch, Division of HIV Prevention, The U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd., Mailstop US8-5, Atlanta, GA, 30329, USA. iwh9@cdc.gov.ORCID http://orcid.org/0000-0002-8948-0500
Mary MullinsTranslation and Evaluation Branch, Division of HIV Prevention, The U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd., Mailstop US8-5, Atlanta, GA, 30329, USA.
Darrel H HigaTranslation and Evaluation Branch, Division of HIV Prevention, The U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd., Mailstop US8-5, Atlanta, GA, 30329, USA.
Linda J KoenigOffice of the Director, Division of HIV Prevention, U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA.
Megan MallettSeKON Enterprise, Inc., Atlanta, GA, USA.
Megan WichserSeKON Enterprise, Inc., Atlanta, GA, USA.
Christa L DenardICF International Inc, Atlanta, GA, USA.
Jayleen GunnHIV Incidence Case Surveillance Branch, Division of HIV Prevention, U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA.
Miriam A M NjiEmory University, Atlanta, GA, USA.
Briana NguyenCollege of Public Health, Virtual Student Federal Service Internship, University of South Florida, Tampa, USA.
Janae MitchellSchool of Public Health and Information Sciences, Virtual Student Federal Service Internship, University of Louisville, Louisville, USA.
Miya PontesBloomberg School of Public Health, Virtual Student Federal Service Internship, Johns Hopkins University, Baltimore, USA.
Madison UnderwoodMilken Institute School of Public Health, Virtual Student Federal Service Internship, George Washington University, Washington, DC, USA.
Theresa Ann SipeTranslation and Evaluation Branch, Division of HIV Prevention, The U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd., Mailstop US8-5, Atlanta, GA, 30329, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Data-to-Care (D2C) is a strategy that uses HIV surveillance data or other data sources to identify out-of-care (OOC) persons with HIV (PWH) and link or re-engage them in care to improve viral suppression (VS). While some evidence suggests D2C is effective, no comprehensive systematic review has been published. This review aims to determine the effectiveness of D2C. A systematic search in five databases (i.e., MEDLINE, EMBASE, PsycINFO, CINAHL, sociological abstracts) identified 3868 U.S. studies published between January 2009 and January 2021 that described D2C interventions and measured HIV care outcomes. Two reviewers screened titles/abstracts, reviewed full reports for eligibility, and abstracted data. Risk of bias was assessed using the Mixed Methods Appraisal Tool, and included studies were synthesized quantitatively and qualitatively (Protocol registered on PROSPERO ID = CRD42020173095). Thirty-four studies with 30 unique interventions were identified. Two different meta-analyses, each with six interventions, found that D2C approached significance in improving engagement in care (Relative Risk (RR) 95% CI 1.18 [0.99 to 1.41]) and VS (RR 95% CI 1.44 [0.99 to 2.09]). Studies that could not be incorporated into the meta-analyses, also showed improvements in engagement in care (median percent [IQI]: 63% [45% to 81%], 18 interventions) and VS (median percent [IQI]: 39% [25% to 57%], 14 interventions). Overall, this systematic review suggests that D2C may enhance HIV care outcomes, emphasizing the need for effective strategies to identify and engage OOC persons in care.

Indexed as

HIV InfectionsHumansTreatment OutcomeData-to-careHIV care continuumHIV surveillanceInterventionLinkage/re-engagement to careOut of care

Identifiers

PMID40668458
PMCPMC12439033

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.