Evidence map›Paper›PMID 40668413›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2026

Respiratory, thoracic, and mediastinal adverse events associated with ticagrelor: A pharmacovigilance study based on FDA adverse event reporting system.

Yuan Zeng, Lin Lu, Tao Jiang, Gang Wei, Wenwu Zheng, Gong Chen

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuan Zeng *Department of Cardiology, The Affiliated Hospital of Southwest Medical University, Luzhou, 446000, Sichuan Province, China.
Lin Lu *Institute of Cardiovascular Research, The Southwest Medical University, Luzhou, 446000, Sichuan Province, China.
Tao JiangDepartment of Cardiology, The Affiliated Hospital of Southwest Medical University, Luzhou, 446000, Sichuan Province, China.
Gang WeiDepartment of Cardiology, The Affiliated Hospital of Southwest Medical University, Luzhou, 446000, Sichuan Province, China.
Wenwu ZhengDepartment of Cardiology, The Affiliated Hospital of Southwest Medical University, Luzhou, 446000, Sichuan Province, China. zhengwenwu888@163.com.
Gong ChenDepartment of Cardiology, The Affiliated Hospital of Southwest Medical University, Luzhou, 446000, Sichuan Province, China. chengong198692@swmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ticagrelor has been authorized for use as an antiplatelet therapy in individuals diagnosed with acute coronary syndrome (ACS). While numerous clinical trials have reported respiratory-related AEs associated with ticagrelor, real-world evidence from large populations remains limited. In this study, we aimed to assess the safety signals of respiratory, thoracic, and mediastinal disorders related to ticagrelor using data from the U.S. Food and Drug Administration Adverse Event Reporting System (FAERS).This study utilized data from the FAERS database spanning 2011 to 2024. The reporting odds ratio (ROR) was used to quantify safety signals of respiratory, thoracic, and mediastinal adverse events associated with ticagrelor. Chi-square (χ

Indexed as

Mediastinal DiseasesPlatelet Aggregation InhibitorsRespiratory Tract DiseasesTicagrelorAcute Coronary SyndromeAdultAdverse Drug Reaction Reporting SystemsAgedAged, 80 and overDatabases, FactualFemaleHumansMaleMiddle AgedPharmacovigilanceUnited StatesPlatelet Aggregation InhibitorsTicagrelorAdverse eventsFAERSPharmacovigilance studyRespiratory systemTicagrelor

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.