ReviewMolecular biology reports2025
Insights into golgi apparatus and centrosome: implications for ciliogenesis.
Review in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Organelle homeostasis disruption: A driving force in the progression of cardiomyopathy (Review).Experimental and therapeutic medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Cilia are highly conserved and microtubule-based organelles protruding from the cell surface. Their assembly and growth are referred to as ciliogenesis. During ciliogenesis, the mother centriole transforms into a basal body, which serves as the template for the ciliary axoneme. Ciliary vesicles required for cilia formation are derived from the Golgi apparatus. Importantly, the physical proximity between the Golgi apparatus and the centrosome is necessary for ciliogenesis. Evidence indicates that programmed death ligand 1 (PD-L1) functions at the centrosome and Golgi apparatus. Its depletion promotes the accumulation of ciliary membrane trafficking proteins and the sensory receptor protein polycystin 2, triggering aberrant ciliogenesis and leading to the development of polycystic kidney disease (PKD). Accordingly, in this review, based on the intimate relationship between the centrosome, Golgi apparatus, and cilia, we summarize in detail the effects of centrosome and its-related proteins, Golgi apparatus and its-associated proteins and Golgi apparatus-centrosome interaction on ciliogenesis. Collectively, understanding the connection between the Golgi apparatus and centrosome provides crucial insights into ciliogenesis mechanisms. Targeting organelle interactions, especially Golgi apparatus-centrosome communication, may represent a promising therapeutic avenue for the prevention and treatment of ciliopathies.
Indexed as
Identifiers
40668383What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.