Evidence map›Paper›PMID 40668375›Full record

ReviewInnere Medizin (Heidelberg, Germany)2025

[Abdominal pain and severely impaired consciousness in a 19-year-old female patient].

Anton Kozlov, Cleo Mybes, Niklas Falk, Maximilian Franz Schulze-Hagen, Stephan Schlecker, Marc Ulrich Becher

Abstract readCase ReportsEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Innere Medizin (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anton KozlovZentrum für Innere Medizin, Medizinische Klinik II für Kardiologie, Rhythmologie, Pneumologie und Internistische Intensivmedizin, Städtisches Klinikum Solingen, Gotenstraße 1, 42653, Solingen, Deutschland. Kozlov.Anton@klinikumsolingen.de.
Cleo MybesZentrum für Innere Medizin, Medizinische Klinik II für Kardiologie, Rhythmologie, Pneumologie und Internistische Intensivmedizin, Städtisches Klinikum Solingen, Gotenstraße 1, 42653, Solingen, Deutschland.
Niklas FalkZentrum für Innere Medizin, Medizinische Klinik III für Geriatrie, Allgemeine Innere Medizin und Nephrologie, Städtisches Klinikum Solingen, Solingen, Deutschland.
Maximilian Franz Schulze-HagenInstitut für Diagnostische und Interventionelle Radiologie, Städtisches Klinikum Solingen, Solingen, Deutschland.
Stephan SchleckerZentrum für Innere Medizin, Medizinische Klinik II für Kardiologie, Rhythmologie, Pneumologie und Internistische Intensivmedizin, Städtisches Klinikum Solingen, Gotenstraße 1, 42653, Solingen, Deutschland.
Marc Ulrich BecherZentrum für Innere Medizin, Medizinische Klinik II für Kardiologie, Rhythmologie, Pneumologie und Internistische Intensivmedizin, Städtisches Klinikum Solingen, Gotenstraße 1, 42653, Solingen, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 19-year-old female patient presented to our clinic with abdominal pain, psychomotor agitation and disorientation. The laboratory analysis revealed severe hyponatremia. Cerebral magnetic resonance imaging (MRI) showed characteristic neuroradiological features of a posterior reversible encephalopathy syndrome (PRES). The detection of a significant increase in the serum concentration of porphyrins confirmed the clinical suspicion of acute intermittent porphyria (AIP). The likely trigger for the sudden AIP exacerbation was the use of levonorgestrel for postcoital contraception. Under treatment with high-dose glucose solution and haem arginate, the abdominal symptoms regressed rapidly. In contrast, neuropsychiatric symptoms improved only gradually, making neurological rehabilitation necessary.

Indexed as

Abdominal PainConsciousness DisordersPorphyria, Acute IntermittentPosterior Leukoencephalopathy SyndromeDiagnosis, DifferentialFemaleHumansHyponatremiaMagnetic Resonance ImagingYoung AdultAcute intermittent porphyriaConfusionHyponatremiaOrganic psychosyndromePosterior reversible encephalopathy syndrome

Identifiers

PMID40668375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.