Evidence map›Paper›PMID 40668353›Full record

SynthesisCardiovascular toxicology2025

Exploring the Impact of Selenium Supplementation on Nutritional, Inflammatory, and Cardiac Function in Chronic Heart Failure Patients: A Novel Approach to Managing Deficiency.

Ladi Kou, Fandong Meng, Guotao Fu, Rongqiang Zhang

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Cardiovascular toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ladi KouAffiliated Hospital, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, People's Republic of China.
Fandong MengCollege of General Medicine, University of Debrecen, Debrecen, 4032, Hajdú-Bihar megye, Hungary.
Guotao FuSchool of Public Health, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, People's Republic of China.
Rongqiang ZhangSchool of Public Health, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, People's Republic of China. zhangrqxianyang@163.com.

Funding

Special R&D Program Project of Chinese Academy of Se-enriched Industry 2020FXZX05-01
6 · The paper itself

Abstract

This study investigated blood selenium (Se) levels in chronic heart failure (CHF) patients and their correlation with cardiac function, followed by a meta-analysis of Se supplementation efficacy. We enrolled 191 CHF patients, measuring blood Se via 2,3-diaminonaphthalene fluorometry. Data were analyzed using SPSS 25.0 and GraphPad Prism 8.0. A systematic review of randomized trials on Se supplementation for CHF was conducted (RevMan 5.3 and Stata 16.0). CHF patients exhibited significantly lower blood Se (P

Indexed as

Deficiency DiseasesDietary SupplementsHeart FailureInflammation MediatorsNutritional StatusSeleniumVentricular Function, LeftAgedBiomarkersChronic DiseaseFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicTreatment OutcomeBiomarkersInflammation MediatorsSeleniumCardiovascular diseasesChronic heart failureMeta-analysisSeleniumSe supplementation

Identifiers

PMID40668353

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.