Thermal therapy of atherosclerotic plaques using ultrasonic phased-array system.

Sha Yuan, Jiwen Hu, Chuangjian Xia, Qinlin Li, Chang Li

Abstract read

In one paragraph

Article in Medical & biological engineering & computing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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2 · The registry

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Sha YuanSchool of Electrical Engineering, University of South China, Hengyang, 421001, China.

Jiwen HuSchool of Mathematics and Physics, University of South China, Hengyang, 421001, China. hu_sanping@163.com.ORCID http://orcid.org/0000-0003-1930-0188

Chuangjian XiaSchool of Mathematics and Physics, University of South China, Hengyang, 421001, China.

Qinlin LiSchool of Electrical Engineering, University of South China, Hengyang, 421001, China.

Chang LiSchool of Mathematics and Physics, University of South China, Hengyang, 421001, China.

Funding

Hengyang science and technology plan projects 202250045335National Nature Science Foundation of China 12274200

6 · The paper itself

Abstract

How to utilize focused ultrasound to achieve rapid, efficient, and safe ablation of atherosclerotic plaques (APs) is a significant challenge in clinical medicine. On the basis of the thermal damage effect of ultrasound on biological tissues, this paper proposes a thermal ablation mode for AP therapy with a single-focus, variable-frequency scanning model using a phased array. An AP model combined with fluid‒solid‒thermal conjugation is established and solved by the finite element method. The results show that the acoustic energy excited by a phased array can be precisely localized at the preset focal points in the plaque, and auto-focused heating is achieved under temperature control at 43 °C. Multiple autofocus scans increase the area of plaque thermal ablation while protecting the normal tissue surrounding the plaque. This model provides a potential treatment option for the thermal ablation of plaques with different depths and sizes.

Indexed as

High-Intensity Focused Ultrasound AblationPlaque, AtheroscleroticUltrasonic TherapyFinite Element AnalysisHumansAtherosclerotic plaqueFocused ultrasoundPhased arrayThermal ablationVariable focusing

Identifiers

PMID40668349

DOI10.1007/s11517-025-03407-w

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.