ArticleThe Journal of infectious diseases2025
Characteristics of Human Metapneumovirus Infection Compared to Respiratory Syncytial Virus and Influenza Infections in Adults Hospitalized for Influenza-Like Illness in France, 2012-2022.
Article in The Journal of infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Global Burden of Human Metapneumovirus in High-Risk Adults: A Systematic Literature Review and Meta-Analysis.Journal of epidemiology and global health · 2026Pooled it
- Hospitalisation Burden of Human Metapneumovirus and Respiratory Syncytial Virus in Adults by Age and Comorbidity Status in Scotland: A Retrospective Analysis.Infectious diseases and therapy · 2026Article
- Characteristics and Risk Factors Associated With Hospitalization and Severe Disease in Patients Aged ≥ 60 Years With Human Metapneumovirus Infection Over Three Consecutive Seasons (2021-2024) in Valladolid, Spain. The VALLAVIRUS Study.Influenza and other respiratory viruses · 2026Article
- Clinical Outcomes and Molecular Epidemiology of Human Metapneumovirus in Romanian Hospitalized Patients.Microorganisms · 2026Article
- Human metapneumovirus: an emerging public health threat and harbinger of a new pandemic.GMS hygiene and infection control · 2025Review
Corrections and comments
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Authors and funding
19 authors.
Funding
Abstract
backgroundWe aimed to compare the characteristics of human metapneumovirus (hMPV) infection with influenza A and B virus (FLUV) and respiratory syncytial virus (RSV) infections in adults hospitalized with influenza-like illness (ILI).
methodsWe conducted a post hoc analysis of adult patients hospitalized with community-acquired ILI who were enrolled in the FLUVAC study at 5 French referral hospitals from 2012 to 2022.
resultsAt least 1 respiratory virus was detected in 3620 of 6618 patients (55%), including FLUV (1524/3620 [42%]), RSV (248/3620 [7%]), and hMPV (162/3620 [5%]). hMPV+ patients, when compared to FLUV+ patients were more likely to develop at least 1 complication (60% [86/143] vs 50% [716/1435]; P = .02), especially acute heart failure, which occurred twice as often in hMPV+ during the hospital stay (22% [32/143] vs 11% [160/1434]; P < .001). The rates of respiratory (30% [43/143] vs 32% [70/216]; P = .73) or cardiac (22% [32/143] vs 15% [33/216]; P = .09) complications did not differ between hMPV+ and RSV+ patients. The in-hospital all-cause death rate was similar among all 3 populations (4% hMPV+, 4% FLUV+, and 5% RSV+).
conclusionsHospitalized hMPV infections affect older patients with multiple chronic conditions who face frequent cardiac and pulmonary complications during hospitalization more frequently than with influenza and similar to RSV.
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