Evidence map›Paper›PMID 40668093›Full record

ArticleThe Journal of infectious diseases2025

The Impact of Chronic Medical Conditions on the Risk of Human Metapneumovirus Hospitalizations in New Zealand Adults, 2012-2015.

Nayyereh Aminisani, Timothy Wood, Ben Waite, Ruth Seeds, Lauren Jelley, Conroy Wong, Q Sue Huang

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Twenty-five years of human metapneumovirus research.Clinical microbiology reviews · 2026
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nayyereh AminisaniWallaceville Science Centre, Institute of Environmental Science and Research.
Timothy WoodWallaceville Science Centre, Institute of Environmental Science and Research.
Ben WaiteWallaceville Science Centre, Institute of Environmental Science and Research.ORCID 0000-0003-0909-8078
Ruth SeedsWallaceville Science Centre, Institute of Environmental Science and Research.
Lauren JelleyWallaceville Science Centre, Institute of Environmental Science and Research.ORCID 0000-0001-5993-6266
Conroy WongDepartment of Respiratory Medicine, Te Whatu Ora, Health NZ Counties Manukau, Auckland.
Q Sue HuangWallaceville Science Centre, Institute of Environmental Science and Research.ORCID 0000-0002-3923-5195

Funding

AstraZeneca GroupCDC HHS U01IP000480IcosavaxNCIRD CDC HHS U01 IP000480New Zealand Ministry of Health
6 · The paper itself

Abstract

backgroundUnlike influenza, information on the risk of human metapneumovirus (HMPV) infections in adults with chronic medical conditions (CMCs) is less robust.

methodsThe SHIVERS project (Southern Hemisphere Influenza and Vaccine Effectiveness Research and Surveillance) performed a population-based surveillance of acute respiratory illness hospitalizations in Auckland, New Zealand, from 2012 to 2015. In this analysis, we linked these surveillance data to population-based administrative data to estimate the age- and ethnicity-adjusted risk of HMPV-associated hospitalization during the study period among adults by certain CMCs: chronic obstructive pulmonary disease, asthma, congestive heart failure, coronary artery disease, cerebrovascular accidents, diabetes mellitus, and end-stage renal disease.

resultsOverall, HMPV hospitalization rates were significantly higher across all ages and ethnic groups among adults with CMCs than those without any condition. In imputed analysis, the CMC with the highest risk of HMPV hospitalization across age groups was congestive heart failure (incidence rate ratio [IRR] range, 7.0-23.0), followed by coronary artery disease (IRR range, 4.2-9.1) and chronic obstructive pulmonary disease (IRR range, 6.7-11.9) in adults aged ≥50 years. The CMC with the highest risk of HMPV hospitalization was congestive heart failure in Māori/Pacific adults and chronic obstructive pulmonary disease in non-Māori/Pacific adults. Adults with ≥2 CMCs had a higher risk than those without CMCs; the risk varied by age group and ethnicity.

conclusionsAdults with specific or ≥2 CMCs are at increased risk of HMPV hospitalizations. Age and ethnicity affect this relationship for some CMCs but not all. Such populations may benefit from future HMPV prevention strategies.

Indexed as

HospitalizationMetapneumovirusParamyxoviridae InfectionsRespiratory Tract InfectionsAdolescentAdultAgedAged, 80 and overChronic DiseaseFemaleHumansMaleMiddle AgedNew ZealandRisk FactorsYoung Adultacute respiratory infectionadultschronic medical conditionshuman metapneumovirusincidence

Identifiers

PMID40668093
PMCPMC12265055

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.