Evidence map›Paper›PMID 40668011›Full record

ArticleApplied and environmental microbiology2025

Metabolic engineering of

Jingfang Sun, Lingling Zhu, Liuping Duan, Furong Li, Shuai Guo, Jinlei Bian, Lin Yang

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Strategy for enhanced production of A40926B0 inSynthetic and systems biotechnology · 2027
    Article
  2. Discovery and functional characterization of endoglucanases fromApplied and environmental microbiology · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jingfang SunSchool of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
Lingling ZhuSchool of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
Liuping DuanSchool of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
Furong LiSchool of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
Shuai GuoSchool of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.ORCID 0009-0008-9605-3727
Jinlei BianSchool of Pharmacy, China Pharmaceutical University, Nanjing, China.ORCID 0000-0003-4552-1195
Lin YangSchool of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.ORCID 0000-0003-1547-8990

Funding

National Key Research and Development Program of China 2019YFA0904900
6 · The paper itself

Abstract

Hydroxytyrosol and salidroside are phenylethanol compounds with significant industrial applications but limited availability due to low-yield natural extraction and complex chemical synthesis. In this study, IMPORTANCE: Hydroxytyrosol and salidroside are valuable natural compounds with strong antioxidant, anti-inflammatory, and neuroprotective properties, widely used in pharmaceuticals, cosmetics, and health supplements. However, traditional extraction from plants is inefficient, and chemical synthesis is costly and environmentally unfriendly. In this study, we engineered

Indexed as

GlucosidesMetabolic EngineeringPhenolsPhenylethyl AlcoholSaccharomyces cerevisiaeFermentation3,4-dihydroxyphenylethanol4-hydroxyphenylethanolGlucosidesPhenolsPhenylethyl Alcoholrhodiolosidehydroxytyrosolphenylethanol compoundsSaccharomyces cerevisiaesalidrosidetyrosol

Identifiers

PMID40668011
PMCPMC12366309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.