ArticleAnnals of medicine2025
Clinical and endoscopic analysis of gastrointestinal bleeding during COVID-19 full-blown pandemic: a retrospective cohort study.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
backgroundAlthough endoscopy is a commonly used technique in patients with gastrointestinal bleeding (GIB), there is currently insufficient evidence to inform clinicians on how to manage patients with gastrointestinal bleeding during COVID-19 full-blown pandemic. Herein, we analyzed the clinical and endoscopic characteristics of GIB in patients hospitalized during COVID-19 full-blown pandemic.
methodsPatients with GIB during the initial stage of COVID-19 pandemic and COVID-19 full-blown pandemic were enrolled and defined as Group 1 and Group 2, respectively. Comeparing the differences in the 30 days mortality, the need for intensive care unit (ICU) level of care, laboratory examination, blood transfusion and anticoagulant therapy, use of non-steroidal anti-inflammatory drugs (NSAIDs), frequency of endoscopy, and examination results between the two groups.
resultsCompared to GIB patients in initial stage of COVID-19 pandemic, prothrombin time (PT) (15.45 s vs 13.84 s,
conclusionDuring COVID-19 full-blown pandemic, the number of patients with GIB increased significantly; these patients were more likely to require ICU admission. Although the endoscopic intervention rate was significantly reduced in COVID-19 patients, there were no significant differences in hospital stay, blood transfusion requirements, rebleeding rate, and mortality.
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