Evidence map›Paper›PMID 40667831›Full record

Trial reportOrthopaedic surgery2025

Biomechanical Advantages of Novel Duet Screws Plus Bilateral Satellite Rods Fixation in the Correction Surgery for Adult Spinal Deformity.

Zhong He, Yi Chen, Zhen Liu, Bo Yang, Benlong Shi, Yu Wang, Zhenhua Feng, Tianyuan Zhang, Xipu Chen, Yong Qiu and 2 more

Erratum issued Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Orthopaedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06144879 (The Biomechanics and Clinical Application of Novel Dual-headed Pedicle Screws in the Corrective Surgery for Spinal Deformity), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06144879 naunknown statusnot on this map

The Biomechanics and Clinical Application of Novel Dual-headed Pedicle Screws in the Corrective Surgery for Spinal Deformity

TypeinterventionalSponsorThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolRan2018 to 2025Enrolled90ConditionsSpine DeformityArmsdouble rods without dual-headed screw, three rods with one dual-headed screw, four rods with two dual-headed screw
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Zhong HeDepartment of Spine Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Yi ChenDepartment of Spine Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Zhen LiuDepartment of Spine Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.ORCID https://orcid.org/0000-0003-2027-8088
Bo YangDepartment of Spine Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Benlong ShiDepartment of Spine Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.ORCID https://orcid.org/0000-0002-0244-8525
Yu WangDepartment of Spine Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Zhenhua FengDepartment of Spine Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Tianyuan ZhangDepartment of Spine Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Xipu ChenDepartment of Spine Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Yong QiuDepartment of Spine Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Xiaodong QinDepartment of Spine Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.ORCID https://orcid.org/0000-0001-7655-2635
Zezhang ZhuDepartment of Spine Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.ORCID https://orcid.org/0000-0001-8569-3595

Funding

Funding for Clinical Trials from Nanjing Drum Tower Hospital 2022-LCYJ-PY-13Funding for Clinical Trials from Nanjing Drum Tower Hospital 2022-LCYJ-PY-39Jiangsu Provincial Key Research and Development Program BE2023658Jiangsu Provincial Medical Innovation Centre of Orthopedic Surgery CXZX202214Nanjing Medical Science and Technology Development Foundation YKK22098National Key Research and Development Program of China 2023YFC2507700National Key Research and Development Program of China 2023YFC2507704National Natural Science Foundation of China U24A20671Natural Science Foundation of Jiangsu Province BK20230147
6 · The paper itself

Abstract

purposeAdult spinal deformity (ASD) patients undergoing pedicle subtraction osteotomy (PSO) with long fusion to the pelvis have a high risk of rod failure at the PSO level or adjacent areas. This study aimed to investigate the biomechanical advantages of novel duet screws (multiaxial screws with dual heads) plus satellite rods in ASD correction using finite element models and cadaveric specimens.

methodsA lumbar-pelvis finite element model was constructed, and Von Mises equivalent stress was used to analyze the structural stress under different fixation constructs. Six human cadaveric spine segments (T11-S2) were selected to validate the finite element results. L3 PSO was performed, with posterior fixation from L1 to pelvis using S2-alar-iliac (S2AI) screws, and satellite rods (L2-L4) were connected to the primary rods using duet screws. Three fixation constructs were evaluated: two rods (Group A), three rods (Group B), and four rods (Group C). In Group B, a biomechanical test was performed on two sides: single rod side (Group B-S) and double rods side (Group B-D). In vitro motion tests were performed under pure moments in lateral bending (LB), flexion/extension (FE), and axial rotation (AR) to measure the range of motion. Rod strain was measured at L3 and S2.

resultsFinite element analysis revealed stress concentration near the PSO site, the screw bases, and the L5-S1 region. The use of duet screws with satellite rods significantly reduced primary rod stress. Cadaveric tests showed that all fixation constructs significantly reduced motion in LB, FE, and AR compared to the intact condition (p < 0.001). No significant differences in total motion or motion at the upper lumbar segments (L1-L3) were observed among the three groups, but differences were found in the lower lumbar segments (L4 and L5) and the sacrum (p < 0.007). Increasing the number of satellite rods significantly decreased rod strain (p < 0.004). Group B-D showed significantly lower rod strain compared to Group B-S (p < 0.042), indicating that satellite rods combined with duet screws were highly effective in reducing primary rod strain at L3. Satellite rods also reduced primary rod strain at the sacrum.

conclusionsThis study supports clinical practice, providing biomechanical evidence for using four-rod constructs with duet screw-based satellite rods in L3 PSO and long fusion. Satellite rods dispersed rod strain, potentially reducing pseudarthrosis and rod breakage at PSO and sacrum without compromising spinal motion.

trial registrationRegistered in ClinicalTrials (NCT06144879).

Indexed as

Bone ScrewsLumbar VertebraeOsteotomyPedicle ScrewsSpinal FusionAdultBiomechanical PhenomenaCadaverFemaleFinite Element AnalysisHumansMaleMiddle AgedRange of Motion, Articularadult spinal deformitycadaveric biomechanicsduet screwsfinite element analysispedicle subtraction osteotomyS2‐alar‐iliac screwssatellite rods

Identifiers

PMID40667831
PMCPMC12318676

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.