Evidence map›Paper›PMID 40667634›Full record

ReviewInternational journal of laboratory hematology2026

Common Hematologic Emergencies-Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias-A Pivotal Role of Clinical Laboratory.

Ganna Shestakova, Nicolas Ulrich Edgar, Anton V Rets

Abstract readReview
In one paragraph

Review in International journal of laboratory hematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ganna ShestakovaUniversity of Utah, Department of Pathology, Salt Lake City, Utah, USA.
Nicolas Ulrich EdgarUniversity of Utah School of Medicine, Salt Lake City, Utah, USA.
Anton V RetsUniversity of Utah, Department of Pathology, Salt Lake City, Utah, USA.ORCID https://orcid.org/0000-0002-2148-162X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services. This review highlights the laboratory's role in identifying conditions associated with increased schistocytes (thrombotic microangiopathies) and acute promyelocytic leukemia. Their detection based on the routine laboratory and morphology methods should trigger appropriate additional laboratory workup including molecular tests, flow cytometry, etc. Hematology laboratory professionals should be skilled to recognize these emergencies and recommend additional workup, playing a critical role in the timely diagnosis and management of life-threatening conditions.

Indexed as

Anemia, HemolyticLaboratories, ClinicalLeukemia, Promyelocytic, AcuteEmergenciesHumansacute promyelocytic leukemiaAPLhematologic emergencyschistocytesthrombotic microangiopathic anemia

Identifiers

PMID40667634
PMCPMC13155284

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.