ArticleThe Journal of cell biology1985
Endothelial plasmalemmal vesicles have a characteristic striped bipolar surface structure.
Article in The Journal of cell biology, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 141 citations in OpenAlex.
- The role of transcytosis in the blood-retina barrier: from pathophysiological functions to drug delivery.Frontiers in pharmacology · 2025Review
- Aspects of Biological Replication and Evolution Independent of the Central Dogma: Insights from Protein-Free Vesicular Transformations and Protein-Mediated Membrane Remodeling.The Journal of membrane biology · 2022Article
- Endothelial Transcytosis in Acute Lung Injury: Emerging Mechanisms and Therapeutic Approaches.Frontiers in physiology · 2022Review
- Lung Endothelial Transcytosis.Comprehensive Physiology · 2020Review
- Unraveling the architecture of caveolae.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Single-molecule Super-resolution Imaging of Phosphatidylinositol 4,5-bisphosphate in the Plasma Membrane with Novel Fluorescent Probes.Journal of visualized experiments : JoVE · 2016Article
- Architecture of the caveolar coat complex.Journal of cell science · 2016Article
- Nanoscale Landscape of Phosphoinositides Revealed by Specific Pleckstrin Homology (PH) Domains Using Single-molecule Superresolution Imaging in the Plasma Membrane.The Journal of biological chemistry · 2015Article
- Cavin family proteins and the assembly of caveolae.Journal of cell science · 2015Review
- Caveolae as plasma membrane sensors, protectors and organizers.Nature reviews. Molecular cell biology · 2013Review
- Article
- Molecular composition and ultrastructure of the caveolar coat complex.PLoS biology · 2013Article
- Targeting and imaging signature caveolar molecules in lungs.Proceedings of the American Thoracic Society · 2009Article
- Vesicle formation and endocytosis: function, machinery, mechanisms, and modeling.Antioxidants & redox signaling · 2009Review
- Belt-like localisation of caveolin in deep caveolae and its re-distribution after cholesterol depletion.Histochemistry and cell biology · 2005Article
- Cell surface orifices of caveolae and localization of caveolin to the necks of caveolae in adipocytes.Molecular biology of the cell · 2003Article
- Mechanism of caveolin filament assembly.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- A comparison of caveolae and caveolin-1 to folate receptor alpha in retina and retinal pigment epithelium.The Histochemical journal · 2001Article
- Heterogeneity of detergent-insoluble membranes from human intestine containing caveolin-1 and ganglioside G(M1).American journal of physiology. Gastrointestinal and liver physiology · 2000Article
- Induction of caveolae in the apical plasma membrane of Madin-Darby canine kidney cells.The Journal of cell biology · 2000Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Capillary endothelial cells have a large population of small (65-80 nm diameter in transmission electron microscopy) vesicles of which a large fraction is associated with the plasmalemma of the luminal and abluminal side. We studied the fine structure and distribution of these plasmalemmal vesicles by high resolution scanning electron microscopy in cultured endothelial cells obtained from bovine adrenal cortical capillaries. Cell monolayers were covered with polylysine-coated silicon chips, split in high potassium buffer, fixed in aldehyde mixtures, and then treated with OsO4 and thiocarbohydrazide. After critical point drying, the specimens were coated with a thin (less than 2 nm) continuous film of chromium. On the cytoplasmic aspect of the dorsal plasmalemmal fragments seen in such specimens, plasmalemmal vesicles appear as uniform vesicular protrusions approximately 70-90 nm in diameter, preferentially concentrated in distinct large fields in which they occur primarily as single units. Individual plasmalemmal vesicles exhibit a striped surface fine structure which consists of ridges approximately 10 nm in diameter, separated by furrows and oriented as meridians, often ending at two poles on opposite sides of the vesicles in a plane parallel to the plasmalemma. This striped surface structure is clearly distinct from the cage structure of coated pits found, at low surface density, on the same specimens. The cytoplasmic aspect of the plasmalemma proper is covered by a fibrillar infrastructure which does not extend over plasmalemmal vesicles but on which the latter appear to be anchored by fine filaments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.