ReviewJournal of pain research2025
Minimally Invasive Lumbar Decompression (MILD) in Patients with Lumbar Spinal Stenosis: A Systematic Review of Randomized and Prospective Trials.
Review in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The MOTION randomized controlled trial for treatment of lumbar spinal stenosis using the percutaneous mild® procedure: 5-year results.Interventional pain medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
Background/Importance: Lumbar spinal stenosis (LSS) remains one of the most common causes of pain and functional disability in patients with chronic pain. Minimally invasive lumbar decompression (MILD) has been shown to reduce pain and improve function with lumbar spinal stenosis. However, very few large studies have evaluated the short- and long-term effects of MILD on functional improvement and pain reduction. Purpose: To evaluate the evidence on the MILD procedure for chronic pain patients with LSS. Methods: A systematic review of randomized and prospective trials investigating the effectiveness of the MILD procedure in managing low back pain and lower extremity pain was performed using PubMed, Medline, Embase, Google Scholar, clinical trial.gov, and Cochrane. We utilized the Cochrane review methodologic quality assessment, GRADE and Interventional Pain Management Techniques - Quality Appraisal of Reliability and Risk of Bias Assessment (IPM-QRB) and IPM-QRB for Nonrandomized Studies (IPM-QRBNR) to guide our data extraction and assessment of study quality methods. Our study summarized and presented the evidence quality on a scale of 1 to 5. Results: Fifteen MILD studies met our inclusion criteria. There were 8 studies that were multicenter prospective trials, and 7 studies were single centers prospective trials. The evidence based on a systematic review of prospective trials investigating the efficacy of the MILD procedure showed a median level 2b evidence with several level 1b studies available. Pain and functional outcome GRADE assessment of studies was high quality. Conclusion: This systematic review suggests that the MILD procedure can be effective in managing chronic pain patients with lumbar spinal stenosis.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.