Evidence map›Paper›PMID 40667481›Full record

ArticleOpen life sciences2025

Optimizing the encapsulation of the refined extract of squash peels for functional food applications: A sustainable approach to reduce food waste.

Rim Ben Mansour, Hanen Falleh, Majdi Hammami, Feriel Ben Hadid, Lilian Barros, Neji Tarchoun, Spyridon A Petropoulos, Riadh Ksouri

Abstract read
In one paragraph

Article in Open life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rim Ben MansourLaboratoire des Plantes Aromatiques et Médicinales, Centre de Biotechnologie de Borj Cedria, BP 901 - Hammam Lif, 2050, Tunis, Tunisia.
Hanen FallehLaboratoire des Plantes Aromatiques et Médicinales, Centre de Biotechnologie de Borj Cedria, BP 901 - Hammam Lif, 2050, Tunis, Tunisia.
Majdi HammamiLaboratoire des Plantes Aromatiques et Médicinales, Centre de Biotechnologie de Borj Cedria, BP 901 - Hammam Lif, 2050, Tunis, Tunisia.
Feriel Ben HadidLaboratoire des Plantes Aromatiques et Médicinales, Centre de Biotechnologie de Borj Cedria, BP 901 - Hammam Lif, 2050, Tunis, Tunisia.
Lilian BarrosCentro de Investigação de Montanha (CIMO) Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253, Bragança, Portugal.
Neji TarchounInstitut Supérieur Agronomique de Chott Mariem, BP 47, 4042 Chott Mériem, Sousse, Tunis, Tunisia.
Spyridon A PetropoulosDepartment of Agriculture, Crop Production and Rural Environment, University of Thessaly, Fytokou Street, 38446, Volos, Greece.
Riadh KsouriLaboratoire des Plantes Aromatiques et Médicinales, Centre de Biotechnologie de Borj Cedria, BP 901 - Hammam Lif, 2050, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Encapsulation of the refined extract from squash fruit peels was evaluated for the design of functional foods with beneficial effects on human health. The percentage of maltodextrin and gum Arabic in the wall material as well as the concentration of the refined extract were the independent variables for the Box Behnken design, and their impact on response variables (total phenolic compound [TPC] content, DPPH activity, the size of particles, and polydispersity index [Pdi]) was evaluated. The obtained emulsions were compared based on their TPC content, as well as their antioxidant activities. Optimum conditions were as follows: maltodextrin percentage of 23.8%, gum Arabic percentage of 27.7%, and phenolic extract percentage of 48.5%. Under these conditions, the response variables were the following: TPC content of 46.01 mg of gallic acid equivalent per gram of extract (mg GAE/g of E); DPPH inhibition percentage of 64.85% at 1 mg/mL, particle size of 571.22 nm, and Pdi of 0.46. Once the emulsion was optimized, we tried to define the combination of variables that produced microcapsules with the highest TPC content and the highest antioxidant activity. Physicochemical parameters and biological activities were also assessed. Microcapsule parameters were a pH of 4.2, a viscosity of 17 mPa/s, and a turbidity of 0.412 NTU (Nephelometric Turbidity Units), and color measurements were

Indexed as

antimicrobial propertiesantioxidant activitybiowaste valorizationencapsulationrefined-extractresponse surface methodologysquash peel

Identifiers

PMID40667481
PMCPMC12260352

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.