Evidence map›Paper›PMID 40667473›Full record

ArticleFrontiers in neurology2025

Predicting hemorrhage expansion in patients with hypertensive intracerebral hemorrhage: the HE-VSD-A2TP score.

Yingying Zhu, Luyang Lin, Wei Wang, Conghui Liu, Peiling Dai, Kai Chen, Jian Chen

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yingying ZhuDepartment of Emergency Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Luyang LinDepartment of Emergency Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Wei WangDepartment of Emergency Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Conghui LiuDepartment of Ultrasound Imaging, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Peiling DaiDepartment of Radiotherapy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Kai ChenDepartment of Cardiovascular and Thoracic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jian ChenDepartment of Emergency Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hematoma expansion (HE) in hypertensive intracerebral hemorrhage (HICH) is significantly associated with patient mortality. Early identification of HE would be planning for appropriate and aggressive management for improving outcome and containing HE. Existing HE prediction models show variable accuracy across settings. To address this limitation, we developed and validate a new predictive model to enhance the accuracy of HE in patients with HICH. Methods: We conducted a retrospective cohort study using data from two centers. The primary outcome was the occurrence of HE within 24 h of symptom onset, defined as an increase in hematoma volume ≥33% or ≥12.5 mL on follow-up imaging. Logistic regression was used to identify independent predictors of HE, and the HE-VSD-A Results: Five hundred and sixty seven patients in the derivation cohort and 378 patients in the validation cohort. The HE-VSD-A Conclusion: The HE-VSD-A2TP score was validated to be an effective tool for identifying patients at risk of HE in patients with HICH. It was a valuable tool for guiding clinical management strategies and potentially improving patient outcomes.

Indexed as

clinical decision-makinghematoma expansionintracerebral hemorrhagepredictive modelrisk stratification

Identifiers

PMID40667473
PMCPMC12260243

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.