ReviewFrontiers in neurology2025
Intrasaccular therapy in wide-neck intracranial aneurysms: a narrative review.
Review in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Endovascular management of internal carotid artery terminus aneurysms: a systematic review and meta-analysis.Neurosurgical review · 2026Pooled it
- The WEVO Technique: A Novel Dual-Device Endovascular Strategy for Non-Geometric Wide Neck Bifurcation Aneurysms.Clinical neuroradiology · 2026Article
- MRI Visibility and MR-DSA Concordance of the Nuvascular Harbor Intrasaccular Occlusion Device: A Preclinical Study.Brain sciences · 2026Article
- Article
- Magnetically-guided, stimuli-responsive microdevices for endovascular therapy.Biomedical microdevices · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The treatment of wide-neck intracranial aneurysms (WNIAs) is a challenge in interventional therapy. Intrasaccular therapy, including intrasaccular flow disruption or formation of a neck bridge within the saccular, has been extensively used recently. The Medina® Embolisation Device, Luna™ Aneurysm Embolisation System, Artisse™ Aneurysm Embolisation System, Contour Neurovascular System™, Neqstent™ Coil Assisted Flow Diverter, Woven EndoBridge (WEB) device, Nautilus™ Intrasaccular System, and Trenza Embolization Device™ have obtained Conformité Européene Mark certification. However, only WEB devices have been approved by the US Food and Drug Administration. The SEAL™ Endovascular Embolization System is approved for sale only in New Zealand. Angiographic results post-procedure and in the follow-up are the main indices used to measure the efficacy of intrasaccular therapy. Complications include ischaemia, thromboembolism, and related haemorrhage. This review summarizes and discusses the efficacy and safety of intrasaccular devices in treating WNIAs. Despite this, complete and satisfactory occlusions are accomplished in most cases of intrasaccular therapy for WNIAs, and the associated complications are typically regarded as acceptable. However, it is important to note that the occlusion rate with intrasaccular therapy is generally lower than that achieved through surgical clipping. Long-term follow-up of intrasaccular therapy and recurrence and retreatment of WNIAs is limited.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.