ArticleFrontiers in nutrition2025
Red blood cell folate and visceral adipose tissue among young and middle-aged American adults.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Dietary index for gut microbiota and DXA-derived visceral adiposity: a cross-sectional study.Journal of health, population, and nutrition · 2026Article
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7 authors.
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Abstract
Background: The relationship between red blood cell (RBC) folate levels and visceral adipose tissue (VAT) accumulation has not been well-explored. This study investigates the association between RBC folate and VAT in young and middle-aged adults in the United States. Methods: A cross-sectional analysis was conducted using data from 7,591 individuals aged 20 to 59 years, drawn from the National Health and Nutrition Examination Survey (NHANES) 2011-2018. VAT was measured using dual-energy X-ray absorptiometry (DXA). RBC folate levels were quantified using a multi-step process combining microbiologic assays and liquid chromatography-tandem mass spectrometry (LC-MS/MS). Multivariate linear regression models were applied to assess the relationship between RBC folate and VAT mass. Results: After adjusting for potential confounders, RBC folate levels were positively associated with VAT mass, with a Conclusion: The association between RBC folate and VAT mass in young and middle-aged American adults follows a J-shaped curve, with a threshold effect observed at an RBC folate level of 397.18 ng/mL. Further research is needed to explore the underlying mechanisms of this association.
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