Evidence map›Paper›PMID 40667365›Full record

ArticlebioRxiv : the preprint server for biology2025

POMPOMS: Crosslinked biomolecular condensates as a versatile platform for multifunctional protein microparticles.

Augene S Park, Erika A Ding, Benjamin S Schuster

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Augene S ParkDepartment of Chemical and Biochemical Engineering, Rutgers, the State University of New Jersey, Piscataway, NJ 08854.ORCID 0000-0001-5930-9369
Erika A DingDepartment of Chemical and Biochemical Engineering, Rutgers, the State University of New Jersey, Piscataway, NJ 08854.ORCID 0009-0006-1305-5408
Benjamin S SchusterDepartment of Chemical and Biochemical Engineering, Rutgers, the State University of New Jersey, Piscataway, NJ 08854.ORCID 0000-0002-6468-8081

Funding

Rutgers Biotechnology Training ProgramT32GM135141 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI ANN M. STOCK, Martin L Yarmush · 2020 to 2026
$3.5M
NIGMS NIH HHS T32 GM135141
6 · The paper itself

Abstract

Protein-based microparticles are promising materials for applications such as biocatalysis and biomolecular capture, yet their fabrication by existing techniques remains challenging due to protein denaturation or lack of spatial control. Here, we present a method for synthesizing microscale protein-based materials by chemically crosslinking biomolecular condensates. Leveraging the liquid-liquid phase separation behavior of intrinsically disordered RGG domains, we sequestered RGG-tagged fusion proteins into droplets, then we solidified them into porous microparticles using the homobifunctional, amine-reactive crosslinker BS

Indexed as

biomolecular capturebiomolecular condensateimmobilized enzymemicroparticlephase separationprotein crosslinking

Identifiers

PMID40667365
PMCPMC12262526

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.