Evidence map›Paper›PMID 40667306›Full record

ArticlebioRxiv : the preprint server for biology2025

The soluble HIV-1 Vpu protein interacts with calmodulin in a Ca

Olamide Ishola, Md Majharul Islam, Elaheh Hadadianpour, Peter P Borbat, Elka R Georgieva

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Olamide IsholaDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Md Majharul IslamDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Elaheh HadadianpourDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Peter P BorbatDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853.
Elka R GeorgievaDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.ORCID 0000-0001-9980-5260

Funding

National Biomedical Resource for Electron-Spin Resonance Spectroscopy (ACERT)R24GM146107 · NIGMS · CORNELL UNIVERSITY · PI BRIAN R CRANE, Jack H Freed · 2022 to 2026
$6.4M
NIGMS NIH HHS R24 GM146107
6 · The paper itself

Abstract

The HIV-1-encoded membrane protein Vpu plays key roles in virus lifecycle. Our lab recently revealed a soluble form of Vpu, and we strived to determine its possible physiological function. Here, we provide solid experimental proof that soluble Vpu interacts with Ca

Indexed as

DEER spectroscopy to study protein-protein complexesprotein conformational changes in protein-protein interactionsoluble HIV-1 Vpu proteinsoluble Vpu-calmodulin interaction

Identifiers

PMID40667306
PMCPMC12262824

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.