Evidence map›Paper›PMID 40667302›Full record

ArticlebioRxiv : the preprint server for biology2025

Hydraulic Activation of the AsLOV2 Photoreceptor.

Shiny Maity, Jackson Sheppard, Hannah Russell, Chung-Ta Han, Leah Epstein, Bruce A Johnson, Brad Price, Ruixian Han, Lokeswara Rao Potnuru, Jinlei Cui and 5 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Shiny MaityDepartment of Chemistry, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0001-7730-6989
Jackson SheppardDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.ORCID 0000-0001-6018-6108
Hannah RussellSUPA School of Physics and Astronomy and BSRC, University of St Andrews, North Haugh, StAndrews, KY16 9SS, UK.ORCID 0000-0003-2850-4369
Chung-Ta HanDepartment of Chemistry, Northwestern University, Evanston, IL 60208, USA.ORCID 0009-0006-0924-3617
Leah EpsteinStructural Biology Initiative, CUNY Advanced Science Research Center, New York, NY 10031, USA.ORCID 0009-0004-9282-0715
Bruce A JohnsonStructural Biology Initiative, CUNY Advanced Science Research Center, New York, NY 10031, USA.ORCID 0000-0001-8445-5368
Brad PriceDepartment of Physics, Institute for Terahertz Science and Technology, University of California Santa Barbara, Santa Barbara, CA 93106, USA.ORCID 0000-0002-2674-4206
Ruixian HanDepartment of Chemistry, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0001-7660-7202
Lokeswara Rao PotnuruDepartment of Chemistry, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0003-1321-9784
Jinlei CuiIntegrated Molecular Structure Education and Research Center (IMSERC), Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-9304-4330
Mark S SherwinDepartment of Physics, Institute for Terahertz Science and Technology, University of California Santa Barbara, Santa Barbara, CA 93106, USA.ORCID 0000-0002-3869-1893
Joan-Emma SheaDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.ORCID 0000-0002-9801-9273
Janet E LovettSUPA School of Physics and Astronomy and BSRC, University of St Andrews, North Haugh, StAndrews, KY16 9SS, UK.ORCID 0000-0002-3561-450X
Kevin H GardnerStructural Biology Initiative, CUNY Advanced Science Research Center, New York, NY 10031, USA.ORCID 0000-0002-8671-2556
Songi HanDepartment of Chemistry, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0001-6489-6246

Funding

G-RISE: Graduate Research Initiative for Student Advancement at The City College of New YorkT32GM136499 · NIGMS · CITY COLLEGE OF NEW YORK · PI RUTH E. STARK · 2020 to 2026
$4.9M
Summer Undergraduate Research Support - Ms. Anastasiia FisiukR01GM106239 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI GARDNER, KEVIN H · 2013 to 2024
$4.5M
NMRFx: An Integrated software suite for macromolecular NMR analysisR01GM123012 · NIGMS · ADVANCED SCIENCE RESEARCH CENTER · PI JOHNSON, BRUCE A · 2017 to 2025
$2.6M
Water as essential building blocks to direct protein structure and functionR35GM136411 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI Songi Han · 2020 to 2026
$2.4M
PAS proteins: Study and application of signaling mechanismsR35GM156296 · NIGMS · ADVANCED SCIENCE RESEARCH CENTER · PI Kevin H Gardner · 2025 to 2026
$1.1M
NIGMS NIH HHS R01 GM106239NIGMS NIH HHS R01 GM123012NIGMS NIH HHS R35 GM136411NIGMS NIH HHS R35 GM156296NIGMS NIH HHS T32 GM136499Wellcome Trust
6 · The paper itself

Abstract

How proteins transduce light into mechanical energy remains a central question in biology. This study tests the hypothesis that blue light activation of the LOV2 (light, oxygen, voltage sensitive) domain of

Identifiers

PMID40667302
PMCPMC12262554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.