Evidence map›Paper›PMID 40667299›Full record

ArticlebioRxiv : the preprint server for biology2025

Due-B Is dispensable for early development and genome duplication in vertebrates.

Courtney G Sansam, Emily A Masser, Duane Goins, Christopher L Sansam

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Courtney G SansamOklahoma Medical Research Foundation, Cell Cycle and Cancer Biology Research Program, Oklahoma City, OK USA.
Emily A MasserOklahoma Medical Research Foundation, Cell Cycle and Cancer Biology Research Program, Oklahoma City, OK USA.ORCID 0000-0002-7934-7175
Duane GoinsOklahoma Medical Research Foundation, Cell Cycle and Cancer Biology Research Program, Oklahoma City, OK USA.ORCID 0000-0003-3154-9007
Christopher L SansamOklahoma Medical Research Foundation, Cell Cycle and Cancer Biology Research Program, Oklahoma City, OK USA.ORCID 0000-0002-0545-2693

Funding

Mechanisms Regulating DNA Replication in the Developing Vertebrate EmbryoR01GM121703 · NIGMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI SANSAM, CHRISTOPHER L · 2017 to 2021
$1.9M
NIGMS NIH HHS R01 GM121703
6 · The paper itself

Abstract

The DNA Unwinding Element-Binding protein (DUE-B) is a Cyclin Dependent Kinase (CDK) and Dbf4-Dependent Kinase (DDK) substrate that has been implicated in the control of DNA replication initiation. Knockdown of DUE-B in HeLa cells perturbs the G1-to-S phase transition and immunodepletion of

Indexed as

developmentDue-BReplicationSld2zebrafish

Identifiers

PMID40667299
PMCPMC12262730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.