Evidence map›Paper›PMID 40667261›Full record

ArticlebioRxiv : the preprint server for biology2025

Effects of Calreticulin Mutations on HLA Class I Expression in Myeloproliferative Neoplasms.

Amanpreet Kaur, Harini Desikan, Grace Pagnucco, Malathi Kandarpa, Moshe Talpaz, Malini Raghavan

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amanpreet KaurDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI.ORCID 0000-0001-6806-8448
Harini DesikanDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI.ORCID 0000-0003-3611-9866
Grace PagnuccoDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI.ORCID 0009-0007-6792-0214
Malathi KandarpaDepartment of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Rogel Cancer Center, Ann Arbor, MI.ORCID 0000-0002-0440-4964
Moshe TalpazDepartment of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Rogel Cancer Center, Ann Arbor, MI.ORCID 0000-0003-3361-3981
Malini RaghavanDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI.ORCID 0000-0002-1345-9318

Funding

Calreticulin-mediated protein folding in health and diseaseR01AI123957 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAGHAVAN, MALINI · 2016 to 2025
$3.7M
NIAID NIH HHS R01 AI123957
6 · The paper itself

Abstract

Calreticulin (CRT) is important for human leukocyte antigen (HLA) class I assembly. Somatic mutations of the CRT gene (

Identifiers

PMID40667261
PMCPMC12262468

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.