Evidence map›Paper›PMID 40667254›Full record

ArticlebioRxiv : the preprint server for biology2025

A Cas12a Toolbox for Rapid and Flexible Group B

G H Hillebrand, S C Carlin, E J Giacobe, H A Stephenson, J Collins, T A Hooven

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

G H HillebrandProgram in Microbiology and Immunology, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.ORCID 0000-0002-3391-4306
S C CarlinDepartment of Pediatrics, Division of Newborn Medicine, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.ORCID 0000-0002-7455-5127
E J GiacobeProgram in Microbiology and Immunology, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.ORCID 0009-0009-8506-011X
H A StephensonDietrich School of Arts and Sciences, University of Pittsburgh, Pittsburgh PA, USA.
J CollinsDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, Louisville KY, USA.
T A HoovenProgram in Microbiology and Immunology, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.ORCID 0000-0003-1959-186X

Funding

Understanding the Host-Microbiome-Therapeutic Triad: Implications for Designing Alternative IntravaginalP20GM125504 · NIGMS · UNIVERSITY OF LOUISVILLE · PI James Tristan Collins · 2018 to 2026
$24.4M
Group B Streptococcus surface determinants of neonatal intestinal colonization and infectionR01AI182835 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Thomas A Hooven · 2024 to 2026
$1.6M
Signal transduction, metabolic shifts, and host interactions during group B Streptococcus infectionR01AI177991 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Thomas A Hooven · 2024 to 2026
$1.4M
Bacterial CRISPR interference to define macrophage responses to group B Streptococcus proteinsR21AI178067 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ARONOFF, DAVID M, HOOVEN, THOMAS A · 2023 to 2024
$451k
NIAID NIH HHS R01 AI177991NIAID NIH HHS R01 AI182835NIAID NIH HHS R21 AI178067NIGMS NIH HHS P20 GM125504
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cas12aCRISPRigenome editingGroup B Streptococcus

Identifiers

PMID40667254
PMCPMC12262448

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.