Evidence map›Paper›PMID 40667245›Full record

ArticlebioRxiv : the preprint server for biology2025

Genome editing of phylogenetically distinct bacteria using portable retron-mediated recombineering.

Alejandro González-Delgado, Laura Bonillo-Lopez, Milo S Johnson, Nastassia Knödlseder, Ching-Chung Ko, Yassir Lekbach, Jee-Hwan Oh, Hemaa Selvakumar, Michael C Wold, Zihan Yu and 9 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Alejandro González-DelgadoGladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.ORCID 0000-0002-8357-3204
Laura Bonillo-LopezUnitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA). Campus de la Universitat Autònoma de Barcelona (UAB), 08193, Bellaterra, Barcelona, Catalonia, Spain.
Milo S JohnsonDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0003-0169-2494
Nastassia KnödlsederDepartment of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Ching-Chung KoDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, 15260, USA.
Yassir LekbachMcKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, 78712, USA.
Jee-Hwan OhDepartment of Food Science, 1605 Linden Dr, University of Wisconsin-Madison, Madison, WI 53706, USA.
Hemaa SelvakumarEnvironmental Genomics and Systems Biology Division, E.O. Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Michael C WoldBioTechnology Institute, University of Minnesota-Twin Cities, St. Paul, Minnesota, USA.
Zihan YuMcKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, 78712, USA.
Virginia AragónUnitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA). Campus de la Universitat Autònoma de Barcelona (UAB), 08193, Bellaterra, Barcelona, Catalonia, Spain.
Jeffrey A GralnickBioTechnology Institute, University of Minnesota-Twin Cities, St. Paul, Minnesota, USA.
Marc GüellDepartment of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Graham F HatfullDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, 15260, USA.ORCID 0000-0002-6705-6821
Benjamin K KeitzMcKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, 78712, USA.
Britt KoskellaDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Vivek K MutalikEnvironmental Genomics and Systems Biology Division, E.O. Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Jan-Peter van PijkerenDepartment of Food Science, 1605 Linden Dr, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0003-4649-5726
Seth L ShipmanGladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.

Funding

Mechanism and application of sugar-induced phage production by the probiotic gut symbiont Lactobacillus reuteriR01AT011202 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI VAN PIJKEREN, JAN-PETER · 2021 to 2025
$2.0M
NCCIH NIH HHS R01 AT011202
6 · The paper itself

Abstract

Advanced genome editing technologies have enabled rapid and flexible rewriting of the

Identifiers

PMID40667245
PMCPMC12262390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.