Evidence map›Paper›PMID 40667201›Full record

ArticlebioRxiv : the preprint server for biology2025

Structures of MmpL complexes reveal the assembly and mechanism of this family of transporters.

Zhemin Zhang, Rakesh Maharjan, William D Gregor, Philip A Klenotic, Edward W Yu

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Zhemin ZhangDepartment of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Rakesh MaharjanDepartment of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
William D GregorDepartment of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Philip A KlenoticDepartment of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Edward W YuDepartment of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

Funding

Intermembrane transport of lipids and metabolites by mycobacterial MmpL protein complexesR01AI187294 · NIAID · UNIVERSITY OF OKLAHOMA · PI Mary Jackson, EDWARD W YU · 2025 to 2026
$1.6M
NIAID NIH HHS R01 AI187294
6 · The paper itself

Abstract

We co-expressed the MmpL5 transporter and MmpS5 adaptor proteins in

Identifiers

PMID40667201
PMCPMC12262633

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.