ArticlebioRxiv : the preprint server for biology2025
MesoSCOUT: A novel tool for revealing mesoscale organization in the white-matter connectome.
Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
We present MesoSCOUT (Mesoscale Structural Connectome Order-complex Unveiling Topology), a framework for characterizing white matter connectivity using a method developed from computational algebraic topology: persistent homology (PH) via clique topology. Applying this method to schizophrenia, we uncover a novel, mesoscale perspective of the differences in the white-matter connectome between healthy controls (HC) and subjects with schizophrenia (SCH). We extract and compare topological motifs found in the structural connectomes of the subjects in the two groups and find significant differences. We explore the overlap of mesoscale structures found in two different datasets,
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Registered trials
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