Evidence map›Paper›PMID 40667099›Full record

ArticlebioRxiv : the preprint server for biology2025

Late onset of striatal projection neuron hyperexcitability in

Lars Nelson, Michael Janeček, Michael Matarazzo, Yi-Chun Shih, Rui T Peixoto

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Lars Nelson
Michael Janeček
Michael Matarazzo
Yi-Chun Shih
Rui T Peixoto

Funding

Mechanisms and pathogenic role of early corticostriatal dysfunction in Shank3B-/- miceR01MH124695 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PEIXOTO, RUI · 2021 to 2025
$2.0M
Role of local interneurons in early cortical dysfunction in Shank3 KO miceR21MH132015 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PEIXOTO, RUI · 2023 to 2023
$437k
NIMH NIH HHS R01 MH124695NIMH NIH HHS R21 MH132015
6 · The paper itself

Abstract

Fragile X Syndrome (FXS), the most common genetic cause of intellectual disability and autism spectrum disorder (ASD), results from silencing of the

Identifiers

PMID40667099
PMCPMC12262218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.