Evidence map›Paper›PMID 40667041›Full record

ArticlebioRxiv : the preprint server for biology2025

Synergistic effects of

Alexandra N Trelle, Jintao Sheng, Edward N Wilson, America Romero, Jennifer Park, Gayle K Deutsch, Sharon J Sha, Michael D Greicius, Katrin I Andreasson, Geoffrey A Kerchner and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexandra N TrelleDepartment of Neurology & Neurological Sciences, Stanford University School of Medicine, Palo Alto, CA 94305.
Jintao ShengDepartment of Psychology, Stanford University, Stanford, CA 94305.
Edward N WilsonDepartment of Neurology & Neurological Sciences, Stanford University School of Medicine, Palo Alto, CA 94305.ORCID 0000-0003-0640-5247
America RomeroDepartment of Neurology & Neurological Sciences, Stanford University School of Medicine, Palo Alto, CA 94305.
Jennifer ParkDepartment of Neurology & Neurological Sciences, Stanford University School of Medicine, Palo Alto, CA 94305.
Gayle K DeutschDepartment of Neurology & Neurological Sciences, Stanford University School of Medicine, Palo Alto, CA 94305.
Sharon J ShaDepartment of Neurology & Neurological Sciences, Stanford University School of Medicine, Palo Alto, CA 94305.
Michael D GreiciusDepartment of Neurology & Neurological Sciences, Stanford University School of Medicine, Palo Alto, CA 94305.
Katrin I AndreassonDepartment of Neurology & Neurological Sciences, Stanford University School of Medicine, Palo Alto, CA 94305.
Geoffrey A KerchnerDepartment of Neurology & Neurological Sciences, Stanford University School of Medicine, Palo Alto, CA 94305.
Elizabeth C MorminoDepartment of Neurology & Neurological Sciences, Stanford University School of Medicine, Palo Alto, CA 94305.
Anthony D WagnerDepartment of Psychology, Stanford University, Stanford, CA 94305.ORCID 0000-0003-0624-4543

Funding

Stanford Alzheimer's Disease Research CenterAdmin Supp: Developing iPSC models for AD and PDP30AG066515 · NIA · STANFORD UNIVERSITY · PI Victor Henderson · 2020 to 2026
$29.0M
Hippocampal-dependent memory decline in aging and early Alzheimer's diseaseR01AG074339 · NIA · STANFORD UNIVERSITY · PI ELIZABETH MORMINO · 2022 to 2026
$6.0M
The Stanford Extreme Phenotypes in Alzheimer's Disease (StEP AD) CohortR01AG060747 · NIA · STANFORD UNIVERSITY · PI GREICIUS, MICHAEL D · 2018 to 2022
$3.4M
High-resolution imaging of hippocampal mechanisms in age-related memory decline.R01AG048076 · NIA · STANFORD UNIVERSITY · PI WAGNER, ANTHONY D · 2014 to 2018
$1.9M
"Eye-tracking and Multimodal Biomarkers to Enhance Detection of Preclinical Alzheimer's Disease in Diverse Populations."K99AG075184 · NIA · STANFORD UNIVERSITY · PI TRELLE, ALEXANDRA NICOLE · 2022 to 2023
$263k
NIA NIH HHS K99 AG075184NIA NIH HHS P30 AG066515NIA NIH HHS R01 AG048076NIA NIH HHS R01 AG060747NIA NIH HHS R01 AG074339
6 · The paper itself

Abstract

Amyloid-β (Aβ) and tau pathology begin accumulating decades before clinical symptoms and are influenced by

Identifiers

PMID40667041
PMCPMC12262513

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.