Evidence map›Paper›PMID 40666961›Full record

ArticlebioRxiv : the preprint server for biology2025

Essentialome-Wide Multigenerational Imaging Reveals Mechanistic Origins of Cell Growth Laws.

Daniel S Eaton, Carlos Sánchez, Luis Gutiérrez-López, Jacob Q Shenker, Youlian Goulev, Brianna R Watson, Véronique Henriot, Ethan C Garner, Quincey A Justman, Jeffrey R Moffitt and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daniel S EatonDepartment of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0003-4790-8254
Carlos SánchezDepartment of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-0909-0909
Luis Gutiérrez-LópezDepartment of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0001-8602-2363
Jacob Q ShenkerDepartment of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0003-2804-4673
Youlian GoulevDepartment of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0003-0370-4567
Brianna R WatsonProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0001-6540-5330
Véronique HenriotDepartment of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
Ethan C GarnerDepartment of Molecular and Cellular Biology, Harvard University, Boston, MA 02138, USA.ORCID 0000-0003-0141-3555
Quincey A JustmanDepartment of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
Jeffrey R MoffittProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0002-3836-3101
Johan PaulssonDepartment of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.

Funding

Limits and Trade-offs of Feedback ControlR01GM081563 · NIGMS · HARVARD MEDICAL SCHOOL · PI Johan Paulsson · 2008 to 2026
$4.9M
Harvard Systems Biology Graduate ProgramT32GM135014 · NIGMS · HARVARD UNIVERSITY · PI DESAI, MICHAEL M, KLEIN, ALLON MOSHE · 2020 to 2024
$1.6M
NIGMS NIH HHS R01 GM081563NIGMS NIH HHS T32 GM135014
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40666961
PMCPMC12262249

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.