ArticleJournal of arrhythmia2025
Early Deterioration of the Right Ventricular Pacing Threshold Predicts the Increase in His-Bundle Pacing Threshold During the Chronic Phase: A Single-Center Retrospective Study.
Article in Journal of arrhythmia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- What is the mechanism of chronic threshold elevation after His-bundle pacing? A histopathological case report suggesting the involvement of fibrin fibrosis.European heart journal. Case reports · 2026Article
- Early Deterioration of the Right Ventricular Pacing Threshold Predicts the Increase in His-Bundle Pacing Threshold During the Chronic Phase: A Single-Center Retrospective Study.Journal of arrhythmia · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: His-bundle pacing (HBP) facilitates physiological ventricular activation. However, concerns about long-term threshold deterioration persist. The predictors of chronic threshold elevation are not yet well established. Methods: Between February 2018 and December 2021, HBP was attempted in 95 patients undergoing pacemaker implantation. Strict success criteria (threshold ≤ 2.0 V/0.4 ms) were applied, and 47 patients with successful HBP were monitored for over 3 years. We assessed pacing thresholds for both the His-bundle and right ventricle (RV) at implantation, 1 week, 1 month, and annually thereafter. Lead shape was evaluated using chest radiography. Patients were categorized into two groups based on their His-bundle pacing threshold: stable (≤ 3.5 V/0.4 ms) and deteriorated (> 3.5 V/0.4 ms). Results: Deterioration in His-bundle pacing thresholds was associated with increased RV pacing thresholds. Deterioration in RV pacing occurred earlier, with significant differences observed at 1 week post-implantation (median RV: 1.87 vs. 3.25 V/0.4 ms, Conclusion: An elevated RV pacing threshold at 1 week post-implantation and lead flexion at implantation may serve as early indicators of long-term deterioration in His-bundle pacing thresholds. When the RV pacing threshold increase is detected, it is important to closely monitor the patient and frequently adjust the output settings to prevent pacing failure.
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