ArticleAlzheimer's & dementia (New York, N. Y.)
Cardiorespiratory fitness modifies the relationship between arterial stiffness and cerebral blood flow independent of physical activity.
Article in Alzheimer's & dementia (New York, N. Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Inflammatory, metabolic, and vascular pathways linking cardiorespiratory fitness to cognition: Results from the IGNITE study.Brain, behavior, & immunity - health · 2026Article
- Sport-specific adaptations in body composition and vascular function: a comparative study of swimmers, tennis players, and wrestlers.Frontiers in sports and active living · 2026Article
- Cardiorespiratory fitness modifies the relationship between arterial stiffness and cerebral blood flow independent of physical activity.Alzheimer's & dementia (New York, N. Y.)Article
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19 authors.
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Abstract
introductionCentral arterial stiffness and cerebral blood flow (CBF) are inversely related. Poor cardiorespiratory fitness (CRF) and low physical activity (PA) are related to both higher arterial stiffness and lower CBF. The present study examined (i) whether CRF or PA moderate the relationship between arterial stiffness and CBF, and (ii) whether the intensity or the type of PA needs to be considered.
methodsParticipants (
resultsThe association between aoPWV and CBF differed by fitness levels, with a negative relationship in the low fitness group and positive relationships in the average and high fitness groups (all DISCUSSION: Average or high fitness, meeting the PA guidelines, and more specifically, moderate intensity and exercise-related PA seem to attenuate the negative relationship between aoPWV on CBF. Highlights: Higher cardiorespiratory fitness (CRF) reduces the negative impact of aortic pulse wave velocity (aoPWV) on cerebral blood flow (CBF)150 min of moderate physical activity (PA) also mitigates this impact, depending on activity typeInnovative methods: use of cardiac magnetic resonance imaging (MRI) for aoPWV assessmentInnovative methods: use of free-breathing acquisition during cardiac MRIInnovative methods: use of cranial 4D flow MRI for CBF assessment.
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