Evidence map›Paper›PMID 40666600›Full record

ArticleCureus2025

Eruption of Petechiae in Liver Failure in an 80-Year-Old Patient: A Case Report.

Abiola Z Odeyinka, Selene M Kizy, Liana N Ly, Kelly M Frasier

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Abiola Z OdeyinkaGeneral Internal Medicine, Macclesfield District General Hospital, East Cheshire NHS Trust, Macclesfield, GBR.
Selene M KizyMedical School, Oakland University William Beaumont School of Medicine, Rochester, USA.
Liana N LyMedical School, College of Osteopathic Medicine, Touro University California, Vallejo, USA.
Kelly M FrasierDermatology, Northwell Health, New Hyde Park, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver failure in the elderly is a clinically challenging condition with increased prevalence, severity, and potential complications due to age-related changes in liver function and other organs. Actual figures identifying the prevalence of liver failure in the elderly population have not been extensively researched and are not readily available. To be effective in curbing the deleterious consequences in this vulnerable population, management must involve early and swift medical interventions such as administration of penicillamine, an antibiotic which acts as an effective metal chelator to manage outcomes in suspected cases of Wilson's disease. There is a huge underdiagnosis problem as symptoms of liver disease may be less obvious in the elderly population, leading to delayed diagnosis and treatment. We present a clinically challenging case of liver failure with petechial rash eruption on the anterior upper chest with acute symptoms of decompensated heart failure in an 80-year-old woman. This case underscores the importance of exploring the differential diagnoses of petechial rash with the absence of abnormal platelets in multimorbid patients. Prompt identification of differential diagnoses leads to choosing management approaches that may improve outcomes in otherwise moribund patients.

Indexed as

acute-on-chronic liver failurealcoholic liver diseasesalpha-1 antitrypsindermisendothelial injuryepstein-barr virus infectionnon-blanching purpurapetechiae rashwilson's disease

Identifiers

PMID40666600
PMCPMC12259480

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.