Evidence map›Paper›PMID 40666579›Full record

ArticleCureus2025

Fully Automatic Artificial Intelligence Liver Anatomy Segmentation in the Management of Colorectal Liver Metastases.

Andrea Chierici, Lisa Guzzi, Sebastien Goffart, Nizar Kamoun, Manuel Gargiulo, Patrick Chevallier, Antonio Iannelli, Rodolphe Anty, Hervé Delingette, Fabien Lareyre and 1 more

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andrea ChiericiDigestive Surgery, Centre Hospitalier Universitaire de Nice, Nice, FRA.
Lisa GuzziNational Institute for Research in Digital Science and Technology (INRIA), Epione Team, Université Côte d'Azur, Sophia Antipolis, FRA.
Sebastien GoffartNational Institute for Research in Digital Science and Technology (INRIA), Epione Team, Université Côte d'Azur, Sophia Antipolis, FRA.
Nizar KamounRadiology, Centre Hospitalier Universitaire de Nice, Nice, FRA.
Manuel GargiuloRadiology, Centre Hospitalier Universitaire de Nice, Nice, FRA.
Patrick ChevallierRadiology, Centre Hospitalier Universitaire de Nice, Nice, FRA.
Antonio IannelliDigestive Surgery, Centre Hospitalier Universitaire de Nice, Nice, FRA.
Rodolphe AntyHepatology, Centre Hospitalier Universitaire de Nice, Nice, FRA.
Hervé DelingetteNational Institute for Research in Digital Science and Technology (INRIA), Epione Team, Université Côte d'Azur, Sophia Antipolis, FRA.
Fabien LareyreVascular Surgery, Centre Hospitalier d'Antibes Juan-les-Pins, Antibes, FRA.
Juliette RaffortClinical Biochemistry, Centre Hospitalier Universitaire de Nice, Nice, FRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionArtificial intelligence is gaining increasing interest in medical image segmentation, including liver cancer. However, the literature lacks model implementation in the setting of colorectal liver metastases for treatment planning. MATERIALS AND

methodsWe collected the portal phase abdominal CT scan images from the Nice University Hospital hepatobiliary oncologic multidisciplinary discussion of 80 patients with colorectal liver metastases, before treatment. Data from 70 patients was exploited to train and test the nnU-Net model to automatically perform parenchyma, portal vein, hepatic veins, cava vein, and colorectal liver metastases segmentation. Data from the remaining 10 patients was used for external validation.

resultsThe Dice score for parenchyma segmentation was 0,964 and 0,955 in the test and validation dataset, respectively. For portal vein segmentation, a centerline Dice (clDice) of 0,758 and 0,736 was highlighted, while for hepatic veins it resulted to be 0,758 and 0,577. Cava vein segmentation showed a clDice of 0,805 and 0,734. Concerning colorectal liver metastases, the Dice score was 0,693 and 0,61.

conclusionThe nnU-Net showed promising segmentation results, especially for liver parenchyma. Its task could be useful to help physicians decide which is the best treatment strategy based on individual anatomical characteristics and disease extension. Training the model on a larger dataset with the same characteristics could help improve segmentation performances.

Indexed as

colorectal cancer liver metastasesdeep learning artificial intelligencehepato-biliary-pancreatic surgerynnu-netoncological general surgery

Identifiers

PMID40666579
PMCPMC12262934

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