ArticleCureus2025
Balo Concentric Sclerosis: A Rare Variant of Multiple Sclerosis With Excellent Response to Early Steroid Treatment.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Case Report: Post-transplant lymphoproliferative disorder mimicking Baló's concentric sclerosis.Frontiers in oncology · 2026Article
- Case Report: Beyond the monophasic myth: relapsing Baló's concentric sclerosis with residual disability.Frontiers in human neuroscience · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Balo concentric sclerosis (BCS) is a rare and aggressive variant of multiple sclerosis (MS), characterized by unique alternating concentric layers of demyelinated and preserved myelin on neuroimaging. We present a case of a 34-year-old male patient with progressive right-sided weakness, whose MRI brain findings confirmed BCS. The patient demonstrated rapid clinical improvement with early initiation of high-dose corticosteroids. The Expanded Disability Status Scale (EDSS) score improved from 6 to 1 within one month, underscoring the importance of timely intervention. Early recognition and prompt treatment are critical to improving outcomes in BCS, as delays can lead to irreversible neurological damage. This case highlights the significant role of early high-dose corticosteroid therapy in achieving clinical improvement and preventing long-term disability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.