Evidence map›Paper›PMID 40666542›Full record

ArticleSSM. Mental health2025

Longitudinal internalizing psychopathology structure in a diverse community sample of Los Angeles adolescents from 9th to 12th grade.

Katherine M Keyes, Megan C Finsaas, Catherine A Gimbrone, Nora C Kelsall, Ahuva L Jacobowitz, Adam M Leventhal, Andrew G Rundle

Abstract read
In one paragraph

Article in SSM. Mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katherine M KeyesDepartment of Epidemiology, Columbia University, USA.ORCID 0000-0002-5624-021X
Megan C FinsaasDepartment of Epidemiology, Columbia University, USA.
Catherine A GimbroneDepartment of Epidemiology, Columbia University, USA.
Nora C KelsallDepartment of Epidemiology, Columbia University, USA.ORCID 0000-0003-2813-3502
Ahuva L JacobowitzDepartment of Epidemiology, Columbia University, USA.
Adam M LeventhalDepartment of Population and Public Health Sciences and Institute for Addiction Science, University of Southern California, USA.
Andrew G RundleDepartment of Epidemiology, Columbia University, USA.

Funding

RESEARCH TRAINING PROGRAM IN PSYCHIATRIC EPIDEMIOLOGYT32MH013043 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Katherine M. Keyes · 1985 to 2026
$11.7M
Temperature, shade, and adolescent psychopathology: understanding how place shapes healthR01MH128734 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KEYES, KATHERINE M., RUNDLE, ANDREW G · 2021 to 2025
$3.4M
Tobacco Use Treatment Research for Vulnerable PopulationsK24DA048160 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Adam Matthew Leventhal · 2019 to 2026
$1.4M
NIDA NIH HHS K24 DA048160NIMH NIH HHS R01 MH128734NIMH NIH HHS T32 MH013043
6 · The paper itself

Abstract

Purpose: Manifestations of internalizing symptoms vary developmentally, particularly during adolescence, but most taxonomies, including modern structural models of psychopathology, do not adequately account for this. Understanding variation in the structure and components of internalizing psychopathology may improve diagnosis. Methods: Self-reported internalizing symptom data were collected from a diverse sample of LA-county adolescents (N = 3368) during each of the four years of high school (grades 9-12). DSM-based symptoms of generalized anxiety, major depression, social phobia, specific phobia, and obsessive-compulsive problems were assessed. Covariance symptom structures were modeled at the four waves using exploratory and confirmatory factor analysis. Results: Based on model fit, parsimony, and meaningfulness, a five-factor model with one factor for each of the DSM-defined internalizing disorders was selected at freshman year (CFI = 0.94), a two-factor fear-and-distress model at sophomore year (CFI = 0.91), and a one-factor model at both junior (CFI = 0.91) and senior years (CFI = 0.92). In freshman year, the nature of the structure is aligned with DSM conceptions of internalizing problems, in sophomore year, the nature of the structure is aligned with fear-distress conceptualizations of internalizing problems as compared to anxiety-depression, and in junior and senior year, the nature of the structure was aligned with a single internalizing dimension. Conclusion: Findings suggest that internalizing problems become increasingly unidimensional across high school. Findings may indicate changes in symptom presentation; accounting for these changes may improve the identification and treatment of internalizing problems among adolescents.

Indexed as

DimensionalityFactor analysisInternalizing symptomsPsychopathologySymptom structure

Identifiers

PMID40666542
PMCPMC12263122

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.