Evidence map›Paper›PMID 40666147›Full record

ReviewFrontiers in public health2025

Between war and pestilence: the impact of armed conflicts on vaccination efforts: a review of literature.

Fausto Ciccacci, Emanuela Ruggieri, Paola Scarcella, Stefania Moramarco, Mariachiara Carestia, Daniele Di Giovanni, Loredana Andreea Silaghi, Anna Maria Doro Altan, Stefano Orlando

Abstract readReview
In one paragraph

Review in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fausto CiccacciDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.
Emanuela RuggieriDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.
Paola ScarcellaLUMSA University, Rome, Italy.
Stefania MoramarcoDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.
Mariachiara CarestiaDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.
Daniele Di GiovanniDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.
Loredana Andreea SilaghiDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.
Anna Maria Doro AltanLink Campus University, Rome, Italy.
Stefano OrlandoDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Armed conflicts profoundly undermine vaccination efforts, disrupting healthcare systems, displacing populations, and enabling the resurgence of vaccine-preventable diseases (VPDs). This narrative review explores the relationship between conflict and immunization coverage through an analysis of 18 studies across diverse regions, including Syria, Nigeria, Afghanistan, Iraq, and Ukraine. Evidence reveals that countries affected by war account for a disproportionate share of global polio and measles cases, often due to damaged infrastructure, interrupted cold chains, and vaccine hesitancy exacerbated by political instability and misinformation. Refugee populations, particularly children, face additional barriers such as poor access, low vaccine literacy, and economic hardship. Despite these challenges, innovative responses have emerged: mobile vaccination teams, negotiated access with armed groups, integration with other humanitarian services, and the use of digital tracking technologies have helped mitigate immunization gaps. However, these are often temporary solutions. Sustainable vaccination coverage requires not only emergency interventions but also long-term conflict resolution. Ceasefires and humanitarian pauses have allowed short-term immunization campaigns, yet their effectiveness is limited without durable peace and systemic rebuilding. The findings highlight the need for coordinated global efforts to protect immunization programs in conflict zones and to uphold vaccination as both a public health priority and a human right.

Indexed as

Armed ConflictsImmunization ProgramsVaccinationVaccination CoverageHumansRefugeesVaccine-Preventable Diseasesconflicthumanitarian healthimmunization (vaccination)preventionrefugee healthvaccinationwar

Identifiers

PMID40666147
PMCPMC12259657

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.