Evidence map›Paper›PMID 40666142›Full record

ArticleTexas Heart Institute journal

Complex Tricuspid and Pulmonic Carcinoid Heart Disease With Timely Surgical Repair.

John Hollowed, Hawkin Woo, Solomon Hamburg, Abbas Ardehali

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Texas Heart Institute journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John HollowedDivision of Cardiology, University of California, Los Angeles, Los Angeles, California.
Hawkin WooDepartment of Medicine, University of California, Los Angeles, Los Angeles, California.
Solomon HamburgDivision of Hematology Oncology, University of California, Los Angeles, Los Angeles, California.
Abbas ArdehaliDivision of Cardiothoracic Surgery, University of California, Los Angeles, Los Angeles, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 63-year-old man with a history of hypertension, prediabetes, and sleep apnea presented with pedal edema, weight loss, and flushing. Laboratory work revealed elevated B-type natriuretic peptide and normocytic anemia. Echocardiography showed right ventricular enlargement, severe tricuspid valve regurgitation, and thickened tricuspid valve leaflets, raising suspicion for carcinoid heart disease. Further testing confirmed a neuroendocrine tumor with liver metastasis. Despite somatostatin therapy, the patient's symptoms were refractory to diuretics. Surgical intervention with tricuspid and pulmonary valve replacement was undertaken. Postoperatively, the patient demonstrated substantial improvement in functional tolerance and quality of life. This case highlights the importance of surgical intervention in advanced carcinoid heart disease.

Indexed as

Carcinoid Heart DiseaseHeart Valve Prosthesis ImplantationPulmonary ValvePulmonary Valve InsufficiencyTricuspid ValveTricuspid Valve InsufficiencyHumansMaleMiddle AgedRecovery of FunctionTime FactorsTreatment Outcomecarcinoid heart diseasespulmonary regurgitationTricuspid regurgitationvalvular heart disease

Identifiers

PMID40666142
PMCPMC12256652

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.