Evidence map›Paper›PMID 40666139›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2025

Factors associated with using penicillins as the first-choice antimicrobial among dentists in Japan: a national cross-sectional study.

Ryuji Koizumi, Masahiro Ishikane, Yoshiki Kusama, Shinya Tsuzuki, Yusuke Asai, Yasuyuki Shimada, Chika Tanaka, Akihiro Kaneko, Norio Ohmagari

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ryuji KoizumiAMR Clinical Reference Center, Disease Control and Prevention Center, National Center for Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan.ORCID https://orcid.org/0009-0003-6248-336X
Masahiro IshikaneAMR Clinical Reference Center, Disease Control and Prevention Center, National Center for Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan.ORCID https://orcid.org/0000-0002-4719-651X
Yoshiki KusamaDepartment of Infectious Diseases, University of Osaka Hospital, Osaka, Japan.ORCID https://orcid.org/0000-0002-7072-2338
Shinya TsuzukiAMR Clinical Reference Center, Disease Control and Prevention Center, National Center for Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan.ORCID https://orcid.org/0000-0001-5732-846X
Yusuke AsaiAMR Clinical Reference Center, Disease Control and Prevention Center, National Center for Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan.ORCID https://orcid.org/0000-0003-2979-3449
Yasuyuki ShimadaOral and Maxillofacial Surgery, National Center for Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan.ORCID https://orcid.org/0000-0001-9181-340X
Chika TanakaAMR Clinical Reference Center, Disease Control and Prevention Center, National Center for Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan.
Akihiro KanekoOral and Maxillofacial Surgery, Ikegami General Hospital, Tokyo, Japan.
Norio OhmagariAMR Clinical Reference Center, Disease Control and Prevention Center, National Center for Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to identify the factors associated with the use of penicillins as the first-choice antimicrobial in Japan's dental clinics. Design: Cross-sectional questionnaire-based survey. Setting: Dental clinics throughout Japan. Participants: Dentists at the participating clinics. Methods: Questionnaires were sent to 1,700 dental care facilities in July 2020, and responses were collected until September 2020. The survey gathered data on clinic characteristics, provision of on-site antimicrobial dispensing, choice of antimicrobials, and knowledge regarding antimicrobial resistance (AMR) and infective endocarditis (IE). Descriptive epidemiology and logistic regression analyses were performed to identify the factors associated with on-site dispensing of penicillins and their use as the first-choice antimicrobial. Results: Responses were obtained from 342 (response rate: 20.1 %) dentists from dental clinics. While 93.9% of respondents were aware of the term "AMR," only 20.8% were familiar with Japan's National Action Plan on AMR. AMR countermeasures were implemented in 79.4% of clinics, but 58.4% of respondents lacked awareness of IE guidelines. In the multivariable logistic regression analyses, "adherence to IE guidelines" (odds ratio: 2.56, Conclusions: There was a low awareness of the National Action Plan and IE guidelines among dentists. Enhancing educational activities and fostering environments that facilitate collaborative decision-making regarding antimicrobial use may help to improve antimicrobial stewardship in Japan's dental clinics.

Identifiers

PMID40666139
PMCPMC12260247

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.