Evidence map›Paper›PMID 40666112›Full record

SynthesisFrontiers in physiology2025

The immediate effects of blood flow restriction training on upper limb muscle strength and fatigue level: a meta-analysis.

Jian Wang, Jie Xu, Haiyang Liu, Lizhu Jiang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jian WangDepartment of Physical Education, Ningbo University of Technology, Ningbo, China.
Jie XuDepartment of Physical Education, Ningbo University of Technology, Ningbo, China.
Haiyang LiuDepartment of Physical Education, Ningbo University of Technology, Ningbo, China.
Lizhu JiangCollege of Education, Ningde Vocational and Technical College, Ningde, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Blood flow restriction training (BFR training) has gained recognition as a potentially effective intervention; however, its specific effects on upper limb strength and fatigue levels remain inadequately explored. This study aims to systematically assess the impact of BFR training on immediate upper limb strength and fatigue through a meta-analytic approach, with the goal of providing empirical evidence to inform its practical implementation in clinical and athletic settings. Methods: Search PubMed, CNKI, Web of Science and EBSCO databases, collect randomized controlled trials (RCTs) on the effects of BFR training on immediate upper limb strength and fatigue degree. Include and exclude literature through the Cochrane risk of bias tool. Employ Revman5.4 and Stata16.0 software for literature quality assessment and statistical analysis. Utilize sensitivity analysis and funnel plots to evaluate the stability of results and publication bias. Results: A total of 32 articles and 524 subjects were incorporated. Meta-analysis revealed that upper limb BFR training significantly increased immediate muscle strength [ Conclusion: Upper limb BFR training can significantly enhance bench press strength. BFR training with 40%-70% 1RM and ≥60% AOP is more likely to promote immediate upper limb strength. Compared with resistance training without compression, exhaustive training may have a negative effect on upper limb muscle strength. BFR training combined with maximal effort and ≥60% AOP can increase the blood lactate value and subjective fatigue degree of the subjects. Systematic Review Registration: http://inplasy.com, identifier: INPLASY202430008.

Indexed as

blood flow restriction trainingblood lactatefatigue levelmuscle strengthrate of perceived exertion

Identifiers

PMID40666112
PMCPMC12259574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.