Evidence map›Paper›PMID 40666098›Full record

ArticleFrontiers in oncology2025

Brian [18F]FDG PET associations of cervical cancer-related peripheral inflammatory markers.

Yao Hu, Yuan Zhong, Yuxiao Hu

Abstract read
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Yao HuDepartment of PET/CT Center, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and the Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Yuan ZhongSchool of Psychology, Nanjing Normal University, Nanjing, Jiangsu, China.
Yuxiao HuDepartment of PET/CT Center, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and the Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The purpose of this study was to explore brain metabolic correlates of peripheral inflammatory markers in patients with cervical cancer (CC). Methods: Cervical cancer (CC) patients (267) without treatments who underwent [18F] Fluorodeoxyglucose ([18F]FDG) positron-emission tomography (PET)/computed tomography (CT) were retrospectively studied. All CC patients were grouped into the International Federation of Gynecology and Obstetrics (FIGO) stage II (n=16), the FIGO stage III (n=160), and the FIGO stage IV (n=91) according to the FIGO stage. According to the median of metabolic tumor volume (MTV) or total lesion glycolysis (TLG) for primary tumor in different FIGO stage, CC patients in different FIGO stage were grouped into the Low_MTV (TLG) group (<median) and High_MTV (TLG) group (≥median). Regression analysis were used to explore the relationships between regional brain glucose metabolism and peripheral inflammatory markers [including Neutrophil-to-Lymphocyte ratio (NLR), Platelet-to-Lymphocyte ratio (PLR), Monocyte-to-Lymphocyte ratio (MLR), and systemic immune-inflammation index (SII)] in whole group, subgroups in different FIGO stage. Results: The MTV and TLG for primary tumor positively correlated with SII ( Conclusion: The glucose metabolism in the dlPFC negatively correlated with peripheral inflammatory markers in CC patients with FIGO stage III or IV may be relevant in the disease severity and vary depending on the disease severity.

Indexed as

cervical cancerperipheral inflammatory markersPETregional brain glucose metabolismtumor metabolic parameters

Identifiers

PMID40666098
PMCPMC12260926

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