Evidence map›Paper›PMID 40666068›Full record

ArticleOxford medical case reports2025

A case of adult-onset Bartter syndrome with transient paraplegia.

Shahzaib Siddiqui, Shayan Ali Irfan, Shahrukh Ahmed, Mirza Mehmood Ali Baig, Jawad Ahmed, Jawed Iqbal

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shahzaib SiddiquiInternal Medicine, Jinnah Sindh Medical University, Rafiqui H.J, Iqbal Shaheed Rd, Karachi Cantonment, Karachi 75510, Pakistan.
Shayan Ali IrfanInternal Medicine, Dow University of Health Sciences, Mission Rd, New Labour Colony Nanakwara, Karachi 74200 Pakistan.
Shahrukh AhmedInternal Medicine, Dow University of Health Sciences, Mission Rd, New Labour Colony Nanakwara, Karachi 74200 Pakistan.
Mirza Mehmood Ali BaigInternal Medicine, Dow University of Health Sciences, Mission Rd, New Labour Colony Nanakwara, Karachi 74200 Pakistan.
Jawad AhmedInternal Medicine, Northwest Health Porter, Valparaiso, Indiana, 46383, United States.
Jawed IqbalDepartment of Communicable Disease Center, Hamad Medical Corporation, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bartter syndrome is a rare inherited renal tubular disorder characterised by metabolic alkalosis, hyperaldosteronism, and salt wasting due to defective salt reabsorption in the ascending loop of Henle. The disease is dominant in the antenatal and neonatal populations and rare in adults. Only a small number of studies present adult-onset Bartter syndrome. We present a case of an adult with transient paraplegia diagnosed with Bartter syndrome. A 22-year-old man presented with sudden bilateral lower limb weakness and cramps for two days, with no history of diarrhoea, vomiting, diuretics, laxatives, or addiction. Biochemical studies revealed hypokalemia, metabolic alkalosis, raised urinary potassium levels and raised serum renin. The potassium replacement therapy was initially ineffective in improving symptoms. The raised urinary calcium to creatinine ratio and normal serum magnesium level were noted. There was no nephrocalcinosis, unlike previously reported cases.

Indexed as

Bartter syndromecase-reporthypokalemiasalt wastingtransient paraplegiayoung adult

Identifiers

PMID40666068
PMCPMC12258025

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