Evidence map›Paper›PMID 40666060›Full record

ArticleOxford medical case reports2025

Catastrophic antiphospholipid syndrome in a young patient: a case report of severe multi-organ and cardiovascular involvement.

Philip Desamour, Sakhr Alshwayyat, Lucila Alvarez, Noor Almasri, Hamdah Hanifa

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philip DesamourFlorida international University Herbert Wertheim College of Medicine, Florida, United States.
Sakhr AlshwayyatResearch Associate, King Hussein Cancer Center, Amman, Jordan.
Lucila AlvarezRoss University School of Medicine, Florida, United States.
Noor AlmasriUniversity of Jordan,  Amman, Jordan.
Hamdah HanifaFaculty of Medicine, University of Kalamoon, Al-Nabk, Syria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Catastrophic Antiphospholipid Syndrome (CAPS) is a rare serious form of APS characterized by thrombosis in multiple organs and a cytokine storm. We report a complex case of a 28-year-old female that tested positive for COVID-19 with a medical history of deep vein thrombosis, pulmonary embolus and systemic lupus erythematosus, with underlying APC, complicating her case of CAPS in multiple organs. Computed Tomography (CT) PE reveled extensive pulmonary emboli and an elevated right/left ventricular ratio (RV/LV). CT of the abdomen and pelvis showed gastritis, ascites and anasarca, fluid accumulation and small bilateral pleural effusions. Urinalysis showed low levels of albumin, urine protein 4+ g, and hyperlipidemia. Laboratory test indicated that the patient has developed a worsening non oliguric acute kidney injury and renal biopsy revealed necrotizing. This is a complex case that contributes to the understanding of CAPS and highlights the challenges of its diagnosis and management.

Indexed as

acute kidney injuryantiphospholipid syndromeembolismpleural effusionsystemic lupus erythematosus

Identifiers

PMID40666060
PMCPMC12258023

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.