ArticleJournal of clinical and translational science2025
From theory to practice - assessing translation of physical fitness research in the emergency department through machine learning and natural language processing.
Article in Journal of clinical and translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: A critical challenge for biomedical investigators is the delay between research and its adoption, yet there are few tools that use bibliometrics and artificial intelligence to address this translational gap. We built a tool to quantify translation of clinical investigation using novel approaches to identify themes in published clinical trials from PubMed and their appearance in the natural language elements of the electronic health record (EHR). Methods: As a use case, we selected the translation of known health effects of exercise for heart disease, as found in published clinical trials, with the appearance of these themes in the EHR of heart disease patients seen in an emergency department (ED). We present a self-supervised framework that quantifies semantic similarity of themes within the EHR. Results: We found that 12.7% of the clinical trial abstracts dataset recommended aerobic exercise or strength training. Of the ED treatment plans, 19.2% related to heart disease. Of these, the treatment plans that included heart disease identified aerobic exercise or strength training only 0.34% of the time. Treatment plans from the overall ED dataset mentioned aerobic exercise or strength training less than 5% of the time. Conclusions: Having access to publicly available clinical research and associated EHR data, including clinician notes and after-visit summaries, provided a unique opportunity to assess the adoption of clinical research in medical practice. This approach can be used for a variety of clinical conditions, and if assessed over time could measure implementation effectiveness of quality improvement strategies and clinical guidelines.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.