Article in Small (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
17 authors.
Vinod KhatriFreie Universität Berlin, Institute of Chemistry and Biochemistry, Takustr. 3, 14195, Berlin, Germany.ORCID 0000-0002-7777-1984
Nico BobackFreie Universität Berlin, Institute of Chemistry and Biochemistry, Takustr. 3, 14195, Berlin, Germany.ORCID 0009-0003-5261-7168
Hassan AbdelwahabFreie Universität Berlin, Department of Physics, Arnimallee 14, 14195, Berlin, Germany.ORCID 0009-0000-2282-1748
Daniela NiemeyerInstitute of Virology, Campus Berlin Mitte, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.ORCID 0000-0002-1897-6365
Tahlia M PalmerFreie Universität Berlin, Institute of Pharmacy, Biopharmaceuticals, Kelchstr. 31, 12169, Berlin, Germany.ORCID 0009-0001-2783-0149
Anil Kumar SahooFreie Universität Berlin, Department of Physics, Arnimallee 14, 14195, Berlin, Germany.
Yannic KerkhoffFreie Universität Berlin, Forschungszentrum für Elektronenmikroskopie, Core-Facility BioSupraMol, Institute of Chemistry and Biochemistry, Fabeckstraße 36a, 14195, Berlin, Germany.ORCID 0000-0002-8126-2082
Kai LudwigFreie Universität Berlin, Forschungszentrum für Elektronenmikroskopie, Core-Facility BioSupraMol, Institute of Chemistry and Biochemistry, Fabeckstraße 36a, 14195, Berlin, Germany.ORCID 0000-0001-6808-8107
Julian HeinzeInstitute of Virology, Campus Berlin Mitte, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.
Dilara BalciFreie Universität Berlin, Institute of Chemistry and Biochemistry, Takustr. 3, 14195, Berlin, Germany.
Jakob TrimpertDepartment of Pathobiology and Diagnostic Medicine, Kansas State University, 1800 Denison Avenue, Manhattan, KS, 66506, USA.
Rainer HaagFreie Universität Berlin, Institute of Chemistry and Biochemistry, Takustr. 3, 14195, Berlin, Germany.ORCID 0000-0003-3840-162X
Tatyana L PovolotskyFreie Universität Berlin, SupraFAB, Department of Biology, Chemistry and Pharmacy, and Department of Physics, Altensteinstr. 23a, 14195, Berlin, Germany.ORCID 0000-0001-5987-777X
Roland R NetzFreie Universität Berlin, Department of Physics, Arnimallee 14, 14195, Berlin, Germany.ORCID 0000-0003-0147-0162
Christian DrostenInstitute of Virology, Campus Berlin Mitte, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.
Daniel C LausterFreie Universität Berlin, Institute of Pharmacy, Biopharmaceuticals, Kelchstr. 31, 12169, Berlin, Germany.ORCID 0000-0003-2009-633X
Sumati BhatiaDepartment of Chemistry, Faculty of Science and Engineering, Swansea University, Singleton Campus, Swansea, SA2 8PP, United Kingdom.ORCID 0000-0002-5123-4937
Funding
Berlin University Alliance CoronaVirusPre-ExplorationProjectDeutsche Forschungsgemeinschaft 431232613-SFB1449/INFDeutsche Forschungsgemeinschaft 434130070-IRTG2662Deutsche Forschungsgemeinschaft 458564133Federal Ministry of Education and Research 13XP511Novo Nordisk Foundation: NNF23SA0088060Royal Society of Chemistry RG∖R1∖241050SupraFAB BioSexSurf
6 · The paper itself
Abstract
Both polysialosides and polysulfates are known to interact with the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. However, a comprehensive site by site analysis of their binding affinities and potential synergistic antiviral effects have not been performed. Here, we report on the synthesis of polysialosides with nanomolar binding affinities to spike proteins of SARS-CoV-2 in solution using microscale thermophoresis. The dendritic polyglycerol based polysialosides dPG
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Polysialosides Outperform Sulfated Analogs for Binding with SARS-CoV-2. · full record | OpenQuestion