Evidence map›Paper›PMID 40665761›Full record

Observational studyJournal of intensive care medicine2025

Severe Community-Acquired Pneumonia: Impact of HIV on Clinical Presentation, Microbiological and Laboratory Findings, and Outcome.

J P Venturas, A Titus, G A Richards, C Feldman

Abstract readObservational Study
In one paragraph

Observational study in Journal of intensive care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

J P VenturasDepartment of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand Medical School, Johannesburg, South Africa.
A TitusIndependent Statistician, Johannesburg, South Africa.
G A RichardsDept of Surgery, Division of Critical Care, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
C FeldmanDepartment of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-6881-8314

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe community-acquired pneumonia (SCAP) is associated with significant morbidity and mortality, but there is a paucity of data regarding these infections in sub-Saharan Africa, especially among people living with HIV (PLWH). This study investigated the impact of HIV on clinical presentation, microbial aetiology, laboratory findings, and outcome of SCAP. This was additional analysis of data from a large, single-centre, retrospective, observational study conducted among consecutive adult patients (≥18 years) admitted to the multidisciplinary ICU at the Charlotte Maxeke Johannesburg Academic Hospital, between 1 July 2007 and 31 May 2019, with SCAP. The current study describes 718 PLWH and 131 HIV-negative cases extracted from the initial cohort. The median age was 37 [IQR 30-46] years with PLWH significantly younger than their HIV-negative counterparts (36 years [IQR 29-44] years vs 52 years [IQR 34-65] years; P < .001). PLWH were more commonly female (P = .053), while more of the HIV-negative patients were male. The median CD

Indexed as

Community-Acquired InfectionsHIV InfectionsPneumoniaAdultAgedCommunity-Acquired PneumoniaFemaleHospital MortalityHumansIntensive Care UnitsMaleMiddle AgedRetrospective StudiesRisk FactorsSouth Africahuman immunodeficiency virusintensive care unitlaboratory findingsmicrobial aetiologymortalityradiographic findingssevere community-acquired pneumoniaseverity of illness

Identifiers

PMID40665761
PMCPMC12464355

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.